Encontrados 33 documentos, a visualizar página 1 de 4
Strengthening Lusophone Collaboration in Cancer Research: Highlights from the F...
Santos, Lúcio Lara; Ribeiro Junior, Howard Lopes; Vilanculo, Lina Mamige; Amodo, Faizana; Selemane, Carlos David Ferreira AloneThe First PALOP/CPLP International Scientific Conference on Cancer was convened in Benguela, Angola, on 25 September 2025, bringing together clinicians, researchers, and policymakers from Portuguese-speaking countries across four continents. The meeting addressed the current landscape of cancer prevention, diagnosis, and treatment in Africa, with particular emphasis on the structural barriers and emerging colla...
Hospital-Based Cancer Registry Audit of the Clínica Sagrada Esperança, Luanda, ...
Vieira Lopes, Lygia; Figueiredo, José; Garcia, Teresa; Costa, Creusa; Costa, Sandra; Santos, Lúcio LaraIntroduction and Objectives: Luanda faces a growing cancer burden alongside a high prevalence of communicable diseases, yet lacks a population-based cancer registry. The Clinica Sagrada Esperanca (CSE), a semi-private institution in Luanda, maintains a hospital-based cancer registry (CSE-HBCR) through a manual data curation process with recognized limitations. This study aimed to (1) perform a structured qualit...
Abdominal Tumor Requiring Surgical Resection in a Young Patient with Neurofibro...
Costa, Victor; Spencer, Hirondina; Borges, Pamela; Afonso, Mariana; Santos, Catarina; Barbosa, Carla; Santos, Lúcio LaraNeurofibromatosis type 1 (NF1) is an autosomal dominant disorder that affects approximately 1 in 3000 births. Retroperitoneal tumors occur in 2%-5% of NF1 patients and pose diagnostic and therapeutic challenges. We report a 25-year-old male from Cape Verde with confirmed NF1 who presented with progressive abdominal pain and a 15 x 11 x 12 cm retroperitoneal mass in the left psoas muscle. He underwent a successf...
A preliminary assessment of a stool-based microRNA profile for early colorectal...
Santos, Daniela A. R.; Eiras, Mariana; Gonzalez-Santos, Miguel; Santos, Marlene; Pereira, Carina; Santos, Lúcio Lara; Dinis-Ribeiro, Mário; Lima, LuísColorectal cancer screening methods are well established worldwide as a fundamental pilar in CRC management, namely through non-invasive faecal occult blood testing. However, the limited sensitivity of faecal occult blood test for detecting precancerous lesions highlights the need to search for alternative tools, such as microRNAs (miRs). The main aim of this study was to identify stoolbased miR profiles for ea...
Deciphering the influence of CD276 glycocode in gastric cancer immunoregulation
Magalhães, Mariana; Dourado-Gonçalves, Martina; Santos, Lúcio Lara; Peixoto, Andreia; Ferreira, José AlexandreGastric cancer (GC) ranks 5th globally in incidence and cancer-related mortality, with advanced-stage 5-year survival rates below 20%1,2, unveiling the need for novel immunotherapies. CD276, an immune checkpoint molecule, is related to immune evasion and tumour progression in GC3-5. In turn, aberrant glycosylation, especially truncated O-glycans, Tn and Sialyl-Tn, correlates with GC aggressiveness and poor prog...
Oncology in the PALOP: a growing challenge
Salamanca, Paulo; Robalo, Magda; Lorenzoni, Cesaltina; Miguel, Fernando; Barbosa, Carla; Santos, Lúcio Lara; Matos, CelsoOncology represents a significant challenge for global public health. In the Portuguese-Speaking African Countries (PALOP), this reality is no different. Cancer not only has a devastating impact on patients but also on their families. The increasing number of cases is putting pressure on the healthcare systems of these nations, which are mostly overwhelmed by infectious diseases and other chronic illnesses. Thi...
RADIATION-INDUCED SARCOMAS: A SURGICAL CHALLENGE
Ferreira Pinto, Paula; Pereira, José Carlos; Correia, Ana Margarida; Baía, Catarina; Marques, Mariana; Silva, José; Martins, Pedro; Santos, Lúcio LaraMalignant peripheral nerve sheath tumors (MPNST) are uncommon, biologically challenging soft tissue sarcomas. The definitive treatment of these tumors is extremely challenging. In 50% of cases, these tumors are associated with type I neurofibromatosis, but in some cases, the cause can be previous treatment with radiotherapy. The present article pretends to report a clinical case of a radiation-induced MPNST sub...
EVALUATION OF THE COSTS OF COLORECTAL CANCER TREATMENT ACCORDING TO PHASE OF CA...
Esgalhado, Filipa; Antunes, Luís; Borges, Marina; Medeiros, Pedro; Sousa, Joaquim Abreu; Santos, Lúcio Lara; Bento, Maria JoséBackground: Colorectal cancer is the second most common cancer in Portugal, which imposes an economic burden in the restricted health care budget. The aim of this study was to estimate the effects of age, stage, gender, Eastern Cooperative Oncology Group performance status, Charlson Comorbidity Index and category of health care activity on the average colorectal cancer treatment costs based on hospital records ...
HIV And Esophageal Cancer In Mozambique: What Can We Learn?
Morais, Atílio; Cossa, Matchecane; Pardival, Abdul; Rodrigues, Jessica; Tivane, Adriano; Germano, Pires; Noormahomed, Emilia; Bento, Maria JoséEsophageal cancer (EC) is a common cancer in Mozambique, with esophageal squamous cell carcinomas (ESCC) being the most frequent subtype of this cancer. Little is known about the impact of the human immunodeficiency virus (HIV) on this pathology. The main goal of this study was to assess the association between EC and HIV infection. Methods: A case-control study was conducted, in 2018, at Maputo Central Hospita...
Identification Of The Crucial Pieces Of Esophageal Cancer Prevention And Early ...
Cossa, Matchecane; Come, Jotamo; Carrilho, Carla; Morais, Atílio; Pereira, Luisa; Santos, Lúcio LaraEsophageal squamous cell carcinoma (ESCC) poses a significant health burden in Mozambique, with high incidence rates and late-stage diagnoses contributing to its lethality. This comprehensive review examines the epidemiology, risk factors, and potential preventive strategies for ESCC in Mozambique. Key risk factors identified include tobacco smoking, alcohol consumption, dietary factors, hot beverage consumptio...