8 documents found, page 1 of 1

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Exuberant Localized Presentation of Mpox Infection

F. Silva, Maria Helena; Ribeiro Dias, Lúcia; Santos, Lurdes

Date: 2024   |   Origin: SPMI Case Reports

Management of ibrutinib treatment in patients with B-cell malignancies: clinica...

Carda, José Pedro; Santos, Lurdes; Mariz, José Mário; Monteiro, Pedro; Gonçalves, Humberto Miguel; Raposo, João; Silva, Maria Gomes da

Ibrutinib, a potent inhibitor of the Bruton tyrosine kinase, has revolutionized the treatment of many B-cell malignancies. Ibrutinib has an established favorable toxicity profile with up to 8 years of experience in clinical trials; however, despite ibrutinib's favorable toxicity profile, dose reductions and treatment discontinuations are becoming more evident in clinical practice, particularly in the setting of...


Protocol for the Prevention of Infections Related to the Treatment of Hematolog...

Silva-Pinto, André; Rocha-Pereira, Nuno; Andrade, Joaquim; Sarmento, António; Santos, Lurdes

Patients with haematological malignancies have a higher incidence of infection compared with the general population. Several factors contribute to this but specially chemotherapy drugs carry different and specific infectious risks. This protocol discusses the prevention of infections in patients who will undergo chemotherapy for the treatment of haematological malignancies. It is divided into: study prior to th...

Date: 2018   |   Origin: Acta Médica Portuguesa

Severe interstitial pneumonia due to murine typhus in a patient returning from ...

Malheiro, Luís; Ceia, Filipa; Alves, João; Carvalho, Ana Cláudia; Sobrinho-Simões, Joana; Sousa, Rita; Sarmento, António; Santos, Lurdes

Murine typhus has been increasingly reported as a cause of fever in returning travelers from Southeast Asia. We report a case of a previously healthy traveler returning from Bali with an non-specific febrile illness which quickly progressed to a severe form of interstitial pneumonia. After a careful epidemiological evaluation and laboratory analysis, murine typhus was diagnosed.


Comparison and Contrast of the Elimination Campaigns for Poliomyelitis and Lepr...

Malheiro, Luís; Pinto, Sofia Correia; Sarmento, Antonio; Santos, Lurdes

As we approach the third decade since the WHO started addressing the eradication of poliomyelitis and leprosy, a reflection of the previous campaigns efficacy and an evaluation of further elimination feasibility is important to adapt and intensify the next steps. We performed a critical review of the poliomyelitis and leprosy eradication campaigns to evaluate their technical and operational feasibilities. Vacci...

Date: 2016   |   Origin: Acta Médica Portuguesa

Seroprevalence survey of Toscana virus infection in Oporto region.

Santos, Lurdes; Cardoso, Maria João; Marinho, Ana Sofia; Guimarães, Tiago; Sarmento, António

Toscana virus (TOSV) endemic in central Italy, has been documented in several European countries of the Mediterranean region. It is a neurotropic virus and in some of these countries studies to investigate seroprevalence have been done. In a recent etiologic study of meningitis we chose 106 of 308 samples to be tested for TOSV using a nested RT-PCR assay, and found six (5.6%) cases of meningitis by Toscana viru...

Date: 2011   |   Origin: Acta Médica Portuguesa

Acute acalculous cholecystitis in a patient with severe malaria.

Carvalho, Dina; Azevedo, Carlos; Coelho, Rui; Ferreira, Alcina; Figueiredo, Paulo; Santos, Lurdes; Sarmento, António

The authors present a clinical case of a 53 years old male admited in an ICU - DI (Intensive care Unit of Infectious Disease) with the diagnosis of severe malaria. He was treated with IV quinine di-hidrocloridrate and doxicicline and developed on the sixth day an acute alithiasic cholecystitis. Transhepatic percutaneous drainage was performed and the patient had good clinical outcome.; The authors present a cli...

Date: 2011   |   Origin: Acta Médica Portuguesa

Impact of acute exercise intensity on plasma concentrations of insulin, growth ...

Ribeiro, Laura; Calhau, Conceição; Pinheiro-Silva, S; Santos, Alejandro; Alçada, Manuel; Guimarães, João; Pina, Alexandra; Maia, Bruno; Pereira, Fábio

Obesity is increasing all over the world, its morbidity justifying a serious effort to improve the situation. Diet and physical exercise constitute major measures to fight obesity. We aimed to investigate the effect of acute exercise intensity over plasma insulin, growth hormone and somatostatin responses. Plasma levels of insulin, growth hormone, somatostatin and glucose were measured at baseline, after 15 min...

Date: 2004   |   Origin: Acta Médica Portuguesa

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