2 documents found, page 1 of 1
The role of N-glycans in regulatory T cells in autoimmunity
Carneiro, P; Vicente, MM; Leite, MI; Santos, ME; Pinho, SS; Fernandes, ÂRegulatory T cells (Tregs) have a key role in the maintenance of immune tolerance and in the prevention of autoimmunity. Recent studies have shown an association between decreased Treg frequency and a deficient suppressive activity with the development of many autoimmune diseases. Although glycosylation, which consists in the addition of glycans to proteins and lipids on the cell surface, is recognized as a cri...
Rapid Experimental Evolution of Pesticide Resistance in C. elegans Entails No C...
Lopes, PC; Sucena, E; Santos, ME; Magalhães, SPesticide resistance is a major concern in natural populations and a model trait to study adaptation. Despite the importance of this trait, the dynamics of its evolution and of its ecological consequences remain largely unstudied. To fill this gap, we performed experimental evolution with replicated populations of Caenorhabditis elegans exposed to the pesticide Levamisole during 20 generations. Exposure to Leva...