7 documents found, page 1 of 1

Interaction of Hoechst 33342 with POPC Membranes at Different pH Values

Hoechst 33342 (H33342) is a fluorescent probe that is commonly used to stain the DNA of living cells. To do so, it needs to interact with and permeate through cell membranes, despite its high overall charge at physiological pH values. In this work, we address the effect of pH in the association of H33342 with lipid bilayers using a combined experimental and computational approach. The partition of H33342 to 1-p...

Inter- and intra-island speciation and their morphological and ecological corre...

The most species-rich and ecologically diverse plant radiation on the Canary Islands is the Aeonium alliance (Crassulaceae). In island radiations like this, speciation can take place either within islands or following dispersal between islands. Aiming at quantifying intra- and inter-island speciation events in the evolution of Aeonium, and exploring their consequences, we hypothesized that (1) intra-island dive...

Gravidez na adolescência

A Preliminary Evaluation of the Pro-Chondrogenic Potential of 3D-Bioprinted Pol...

Degeneration of articular cartilage (AC) is a common healthcare issue that can result in significantly impaired function and mobility for affected patients. The avascular nature of the tissue strongly burdens its regenerative capacity contributing to the development of more serious conditions such as osteoarthritis. Recent advances in bioprinting have prompted the development of alternative tissue engineering t...

Síntese e estudos da atividade antitumoral de complexos de ruténio-salen.

Dissertação de Mestrado em Química Medicinal apresentada à Faculdade de Ciências e Tecnologia; O cancro da mama e o cancro colorretal são, respetivamente, o segundo e terceiro tipos de cancro com maior incidência e, por isso, estão associados a elevadas taxas de mortalidade em todo o mundo. Embora exista uma série de fármacos quimioterapêu-ticos usados para o tratamento destas doenças, que incluem os complexos ...

Design, Stone, Wood and Natural Fiber: An experiment for Development of new pro...

The study presents an experiment with three different natural raw materials:stone, wood and natural fiber for products development, serving commercial environments with a regional focus: hotels and restaurants. It aimed to train the students of the UFAM Design Course to design decorative objects through the technology and professional experience of four teaching and research institutions in Brazil and Europe. I...

Fire effects on capsules and encapsulated seeds from Eucalyptus globulus in Por...

Eucalyptus globulus is native to Australia and currently one of the most cultivated hardwood species worldwide. The adaptation of E. globulus to fire-prone habitats has been linked to fire as a driver for regeneration and subsequent naturalization in Mediterranean-type regions. We studied the effect of fire on capsules and encapsulated seeds of E. globulus Labill. in the canopy and on the ground, aiming to asse...