2 documents found, page 1 of 1
Mechanical strength study of cranial implants
Santos, Pedro OliveiraThe human head is sometimes subjected to impact loads which lead to the skull fracture or other injuries that require the removal of part of the skull - craniectomy. Consequently, the removed portion is then replaced using autologous bone or alloplastic material. This work focuses on developing a cranial implant to fulfill the defect created on the skull and then study its mechanical performance, integrating it...
Atherosclerosis and bone loss in humans: results from deceased donors and from ...
Carmona-Fernandes, Diana; Barreira, Sofia; Leonardo, Natacha; Casimiro, Renata I.; Castro, Alice M.; Santos, Pedro Oliveira; Fernandes, António N.Background and Aims: Atherosclerosis and osteoporosis share common risk factors, as well as inflammatory mechanisms. Our aim was to understand how atherosclerotic lesions are related with disturbances in bone. Methods: Gene expression of pro-inflammatory and bone metabolism related proteins (IL-1β, IL-6, IL-17A, TNF, RANKL, OPG, COL1, CTSK, OCL, TRAP, CBFA1, DKK1, SOST, ADIPOQ, and ADIPOR1) were analyzed in art...