94 documents found, page 1 of 10
Adult Nephronophthisis – An OverlookedCause of Chronic Kidney Disease: Two Case...
Paes de Faria, Vitória; Dias, Joana; Falcão Reis, Cláudia; Santos, Sofia; Gomes, Ana MartaNephronophthisis is the most common monogenic cause of chronic kidney failure within the first three decades of life. Adult-onset disease remains largely underdiagnosed because of its subtle and nonspecific clinical presentation. We report two families with adult-onset chronic kidney disease (CKD), of undetermined aetiology who were subsequently diagnosed with a homozygous pathogenic variant in TTC21B, c.626C&g...
Descobrindo a Educação Inclusiva através dos olhos dos alunos de Territórios Ed...
Kamp, Marcia; Carvalho, Carolina; Marchão, Amélia; Martins, Maria José D.; Santos, SofiaNo âmbito da educação inclusiva, Portugal tem desenvolvido medidas para diminuir assimetrias socioeconómicas e geográficas, nomeadamente, o programa Territórios Educativos de Intervenção Prioritária (TEIP), cuja monitorização deve integrar a voz ativa dos principais intervenientes e incluir os alunos. Contudo, há poucas evidências da voz dos alunos sobre as escolas TEIP. No presente estudo, o objetivo foi anali...
Evaluation of the effect of mouthwashes on titanium alloy miniscrews: a systema...
Es-Samti, Lamiae; Oliveira, Ana Catarina; Santos, Sofia; Santos, Catarina; Sousa-Santos, PrimaveraOrthodontic miniscrews (MSs) are increasingly used in orthodontics, providing good treatment results, particularly Ti-6Al-4V MSs. Sometimes, after placing the MSs, orthodontists prescribe mouthwashing to avoid risk of infection, thus ensuring good stability and optimizing the final treatment result. The aim of this review is to analyze the effects of chlorhexidine (CHX) and sodium fluoride (NaF) mouthwashes on ...
Large language models in automated repair of haskell type errors
Santos, Sofia; Saraiva, João; Ribeiro, FranciscoThis paper introduces a new method of Automated Program Repair that relies on a combination of the GPT-4 Large Language Model and automatic type checking of Haskell programs. This method identifies the source of a type error and asks GPT-4 to fix that specific portion of the program. Then, QuickCheck is used to automatically generate a large set of test cases to validate whether the generated repair behaves as ...
Relatório de Ensino Clínico - Integração à Vida Profissional
Santos, SofiaO presente relatório surge no âmbito da unidade curricular: Ensino Clínico (EC)- Integração à Vida Profissional (IVP), do 4º Ano/ 2º Semestre do Curso de Licenciatura em Enfermagem da Escola Superior de Saúde, do Instituto Politécnico da Guarda, no ano letivo 2022/2023. Este EC foi realizado em dois contextos diferentes, um em Contexto de Cuidados de Saúde Hospitalares (CSH) e outro em Contexto de Cuidados de S...
Uma agenda da UE em matéria de luta contra o terrorismo : questões jurídicas
Santos, SofiaLusíada. Direito. - ISSN 2182-4118. S.2, n. 31 (2024).
An in vivo model of ischemic stroke to study potential pharmacological targets
Mendes, Priscila; Solas, João; Santos, Sofia; Boralho, Adelaide; Ratilal, Bernardo; Mateus, Vanessa; Rocha, JoãoBackground: Ischemic Stroke (IS) is caused by a focal disruption in cerebral blood flow due to the occlusion of a blood vessel, most commonly the middle cerebral artery (MCA) [1]. The ischemic cascade results in neuronal death and inflammatory response, including in situ microglia activation. Inflammation is a double‐edged sword; it can cause tissue injury but can also help in the tissue repair of the brain [2]...
Neurobehavioral sex-related differences in Nf1+/- mice: female show a "camoufla...
Santos, Sofia; Martins, Beatriz; Sereno, José; Martins, João; Castelo-Branco, Miguel; Gonçalves, JoanaBackground Neurofibromatosis type 1 (NF1) is an inherited neurocutaneous disorder associated with neurodevelopmental disorders including autism spectrum disorder (ASD). This condition has been associated with an increase of gamma-aminobutyric acid (GABA) neurotransmission and, consequently, an excitation/inhibition imbalance associated with autistic-like behavior in both human and animal models. Here, we explor...
An in vivo model of ischemic stroke to study potential pharmacological targets
Mendes, Priscila; Solas, João; Santos, Sofia; Fernandes, Adelaide; Ratilal, Bernardo; Mateus, Vanessa; Rocha, JoãoBackground: Ischemic Stroke (IS) is caused by a focal disruption in cerebral blood flow due to the occlusion of a blood vessel, most commonly the middle cerebral artery (MCA)—the ischemic cascade results in neuronal death and inflammatory response, including in situ microglia activation. Inflammation is a double‐edged sword; it can cause tissue injury but can also help in the tissue repair of the brain. The onl...
Dificuldades dos enfermeiros no cuidar espiritual da pessoa em situação paliati...
Santos, Sofia; Feiteira, Bruno; Marques, AlbertinaObjetivo: Mapear a evidência científica relativa às dificuldades dos enfermeiros no cuidar espiritual da pessoa em situação paliativa. Método: Estudo do tipo Scoping Review, com base nas recomendações PRISMA-ScR e do protocolo definido pelo Joanna Briggs Institute. Pesquisa em 4 bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), National Library of Medicine (PUBMED), Cummul...