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Tumor suppressor p53 protein expression : prognostic significance in patients w...
Duarte, Fernando Barroso; Gonçalves, Romelia Pinheiro; Barbosa, Maritza Cavalcante; Rocha Filho, Francisco Dário; Santos, Talyta Ellen de Jesus dosBackground: At the time of diagnosis, more than 50% of patients with myelodysplastic syn- drome have a normal karyotype and are classified as having a favorable prognosis. However, these patients often show very variable clinical outcomes. Furthermore, current diagnostic tools lack the ability to look at genetic factors beyond karyotyping in order to determine the cause of this variability. Objective: To evalua...
Date: 2014
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Origin: Oasisbr