94 documents found, page 1 of 10
Design of natterins-based peptides improves antimicrobial and antiviral activities
de Cena, Gabrielle L.; Tada, Dayane B.; Lucchi, Danilo B. M.; Santos, Tiago; Heras, Montserrat; Juliano, Maria; Torres Braconi, CarlaThe biochemical analysis of animal venoms has been intensifying over the years, enabling the prediction of new molecules derived from toxins, harnessing the therapeutic potential of these molecules. From the venom of the fish Thalassophryne nattereri, using in silico methods for predicting antimicrobial and cell-penetrating peptides, two peptides from Natterins with promising characteristics were synthesized an...
New forecast tools to enhance the value of VRE on the electricity markets : 2nd...
Estanqueiro, Ana; Couto, António; Schimeczek, Christoph; Lopes, Duarte; Algarvio, Hugo; Preto, Isabel; Kochems, Johannes; Santos, Tiago; Faria, RicardoABSTRACT: The present deliverable was developed as part of the research activities of the TradeRES project Task 4.4 - Enhancing the value of VRE on the electricity markets with advanced forecasting and ramping tools edition 2. This report presents the second edition of deliverable 4.9, which consists of the description and implementation of the forecasting models aiming to identify and explore the time synergie...
Enhanced Antimalarial Activity of Extracts of Artemisia annua L. Achieved with ...
Ferreira, Ana M.; Sales, Isabela; Santos, Sónia A.O.; Santos, Tiago; Nogueira, Fátima; Mattedi, Silvana; Pinho, Simão; Coutinho, João A.P.Artemisinin, a drug used to treat malaria, can be chemically synthesized or extracted from Artemisia annua L. However, the extraction method for artemisinin from biomass needs to be more sustainable while maintaining or enhancing its bioactivity. This work investigates the use of aqueous solutions of salts and ionic liquids with hydrotropic properties as alternative solvents for artemisinin extraction from Arte...
The Impact of a 12-Week Workplace Physical Activity Program on the Quality of L...
Rocha, Fernanda Viomar; Matos, Rui; Monteiro, Diogo; Jacinto, Miguel; Antunes, Raul; Amaro, Nuno; Santos, Tiago; Rodrigues, FilipeOffice workers frequently display behavioral patterns marked by extended periods of sedentary and seated work. In this context, the implementation of a workplace exercise program has been shown to be effective in mitigating health-related risk factors. This study aimed to evaluate the impact of a 12-week workplace exercise program on the quality of life of employees whose primary occupational duties involve pro...
Antimalarial activity of aqueous extracts of Nasturtium (Tropaeolum majus L.) a...
Pintão, Ana Maria; Santos, Tiago; Nogueira, FátimaMalaria remains an important and challenging infectious disease, and novel antimalarials are required. Benzyl isothiocyanate (BITC), the main breakdown product of benzyl glucosinolate, is present in all parts of Tropaeolum majus L. (T. majus) and has antibacterial and antiparasitic activities. To our knowledge, there is no information on the effects of BITC against malaria. The present study evaluates the antim...
A 3D-Printed Ceramics Innovative Firing Technique: A Numerical and Experimental...
Santos, Tiago; Ramani, Melinda; Devesa, Susana; Batista, Catarina; Franco, Margarida; Duarte, Isabel Catarina; Costa, Luís; Ferreira, NelsonAdditive manufacturing (AM), also known as three-dimensional (3D) printing, allows the fabrication of complex parts, which are impossible or very expensive to produce using traditional processes. That is the case for dinnerware and artworks (stoneware, porcelain and clay-based products). After the piece is formed, the greenware is fired at high temperatures so that these pieces gain its mechanical strength and ...
Nanotechnology applications in sepsis: essential knowledge for clinicians
Vasconcelos, Inês; Santos, TiagoSepsis is a life-threatening condition caused by a dysregulated host response to an invading pathogen such as multidrug-resistant bacteria. Despite recent advancements, sepsis is a leading cause of morbidity and mortality, resulting in a significant global impact and burden. This condition affects all age groups, with clinical outcomes mainly depending on a timely diagnosis and appropriate early therapeutic int...
Testing the Associations between Coping, Mental Health, and Satisfaction with L...
Rodrigues, Filipe; Morouço, Pedro; Santos, TiagoThe present study aimed to explore the relationships between coping strategies, symptoms of depression, anxiety, and stress, and satisfaction with life among Portuguese workers. A sample of 402 participants (207 male, 195 female), ranging in age from 18 to 70 years (M = 32.90, SD = 11.75), was included in the study. Participants reported varying levels of work experience, ranging from 1 to 45 years (M = 10.62, ...
A 3D-Printed Ceramics Innovative Firing Technique: A Numerical and Experimental...
Santos, Tiago; Ramani, Melinda; Devesa, Susana; Batista, Catarina; Franco, Margarida; Duarte, Isabel; Costa, Luis; Ferreira, Nelson; Alves, NunoAdditive manufacturing (AM), also known as three-dimensional (3D) printing, allows the fabrication of complex parts, which are impossible or very expensive to produce using traditional processes. That is the case for dinnerware and artworks (stoneware, porcelain and clay-based products). After the piece is formed, the greenware is fired at high temperatures so that these pieces gain its mechanical strength and ...
Projeto em contexto de estágio – Armis Group (Porto)
Santos, TiagoO presente documento tem como objetivo relatar o trabalho realizado no projeto em contexto de estágio realizado na empresa Armis Group, na área de sistemas de informação. Este consistiu no desenvolvimento de uma plataforma web, para dar suporte à criação e gestão de campanhas de fidelização de clientes e substituir um produto já existente que é suportado por terceiros. Esta nova plataforma web possibilita a ges...