35 documents found, page 1 of 4
Saliva protein composition relates with inter-individual variations in bread se...
Lamy, E; Santos, V; Barrambana, S; Simões, C; Carreira, L; Infante, P; Capela e Silva, FSensory perception of starch‐based products associates with salivary α‐amylase enzymatic activity. Besides this, other proteins relate to taste sensitivity and oral food processing. As such, the participation of different salivary constituents in starch‐rich food's sensory evaluation cannot be excluded. This study aims to identify salivary proteins altered by bread mastication and correlated with sensory rating...
Decrease in Stigma Towards Mental Illness in Portuguese Medical Students After ...
Vilar Queirós, R; Santos, V; Madeira, NIntroduction: Stigma towards mental illness is considered a key obstacle to the provision of medical care to psychiatric patients. This is not only present in the general population but also among healthcare professionals. Therefore, medical students could be a target population for stigma prevention measures. The aim of this study is to assess the evolution of the attitudes of medical students from the Faculty...
Management of Coronavirus Disease 2019 Patients With Lung Cancer: Experience Fr...
Coelho, DB; Santos, V; Araújo, D; Bastos, HN; Magalhães, A; Hespanhol, V; Queiroga, H; Martins, N; Fernandes, GBackground: Cancer patients appear to be at a higher risk of complications from coronavirus disease 2019 (COVID-19). Specific data related to lung cancer (LC) patient management, active treatment, and/or recent diagnosis are still very limited. Here, we aimed to investigate the clinical presentation, baseline features, and clinical outcomes of LC patients with COVID-19. Methods: A retrospective case study was p...
The Role of Liquid Biopsy in Early Diagnosis of Lung Cancer
Freitas, C; Sousa, C; Machado, F; Serino, M; Santos, V; Martins, N; Teixeira, A; Cunha, A; Pereira, T; Oliveira, HP; Costa, JL; Hespanhol, VLiquid biopsy is an emerging technology with a potential role in the screening and early detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and are currently under ongoing investigation. In this article, we review the available data on the use of circulating biomarkers for the early detection of lung cancer, focusing on the circulating tumor cells, circulating cell-free DNA,...
Risk Calculators in Bipolar Disorder: A Systematic Review
Silva Ribeiro, J; Pereira, D; Salagre, E; Coroa, M; Santos Oliveira, P; Santos, V; Madeira, N; Grande, I; Vieta, EIntroduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversi...
Hypersensitivity pneumonitis: Main features characterization in a Portuguese co...
Santos, V; Martins, N; Sousa, C; Jacob, M; Padrão, E; Melo, N; Mota, PC; Bastos, HN; Guimarães, S; Moura, CS; Sokhatska, O; Cunha, R; Pereira, JHypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) which varies in prevalence across the world, depending on disease definition, diagnostic methods, exposure type and intensity, geographical environments, agricultural and industrial practices, and host risk factors. This study aimed to deepen knowledge about HP's clinical characteristics, diagnosis and functional and imaging features in a c...
Prognostic Effect and Modulation of Cardiac Sympathetic Function in Heart Failu...
Ilhão Moreira, R; Abreu, A; Portugal, G; Oliveira, L; Oliveira, MM; Rodrigues, I; Coutinho Cruz, M; Silva Cunha, P; Santos, V; Santa Clara, HBackground: Cardiac autonomic dysfunction as assessed by 123I-metaiodobenzylguanidine (123I-mIBG) scintigraphy is associated with poor prognosis in heart failure (HF) patients. Although cardiac resynchronization therapy (CRT) has emerged as an effective therapy in improving outcomes on HF patients, its effect on cardiac sympathetic nervous function is still not fully understood. We aimed to study the value of p...
Relationship of Left Ventricular Global Longitudinal Strain with Cardiac Autono...
Coutinho Cruz, M; Abreu, A; Portugal, G; Santa-Clara, H; Silva Cunha, P; Oliveira, MM; Santos, V; Oliveira, L; Rio, P; Rodrigues, I; Morais, LABACKGROUND: Heart failure (HF) is associated with cardiac autonomic denervation (AD), which can be non-invasively assessed by 123I-metaiodobenzylguanidine (123I-mIBG) scintigraphy and has prognostic implications. We aimed to study the relationship between myocardial contractility assessed by global longitudinal strain (GLS) and AD assessed by 123I-mIBG scintigraphy in advanced HF. METHODS/RESULTS: BETTER-HF is ...
A Post Hoc Analysis on Rhythm and High Intensity Interval Training in Cardiac R...
Melo, X; Abreu, A; Santos, V; Silva Cunha, P; Oliveira, MM; Pinto, R; Mota Carmo, M; Fernhall, B; Santa-Clara, HObjectives. Evaluate the effects of a 6-month High Intensity Interval Training (HIIT) program on (1) functional capacity and health-related quality of life, (2) multiple blood biomarkers, (3) echocardiographic parameters, and (4) exercise performance, in patients in cardiac resynchronization therapy (CRT) stratified by the presence of atrial fibrillation (AF), targeting the following questions: (1) Does CRT pro...
High-Intensity Interval Training in Cardiac Resynchronization Therapy: a Random...
Santa-Clara, H; Abreu, A; Melo, X; Santos, V; Silva Cunha, P; Oliveira, MM; Pinto, R; Mota Carmo, M; Fernhall, BAIMS: To determine the effects of high-intensity interval training (HIIT) following cardiac resynchronization therapy (CRT) implantation in patients with chronic heart failure (CHF), on noninvasive estimates of systolic ventricular function, exercise performance, severity of symptoms and quality of life. METHODS: Cardiopulmonary exercise testing, resting transthoracic echocardiogram and health-related quality o...