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Antifungal activity of liriodenine on clinical strains of Cryptococcus neoforma...

Levorato-Vinche,Adriele Dandara; Melhem,Marcia de Souza Carvalho; Bonfietti,Lucas Xavier; de-la-Cruz-Chacón,Iván; Boaro,Carmen Sílvia Fernandes

Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC dai...

Date: 2022   |   Origin: Oasisbr

Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis...

Vinche,Adriele Dandara Levorato; de- la-Cruz-Chacón,Iván; González-Esquinca,Alma Rosa; Silva,Julhiany de Fátima da; Ferreira,Gisela

Abstract Background: Endemic systemic mycoses remain a health challenge, since these opportunistic diseases are increasingly infecting immunosuppressed patients. The simultaneous use of antifungal compounds and other drugs to treat infectious or non-infectious diseases has led to several interactions and undesirable effects. Thus, new antifungal compounds should be investigated. The present study aimed to evalu...

Date: 2020   |   Origin: Oasisbr

Effects of propofol in lipid-based emulsion and in microemulsion on the inciden...

Paço,Cristian Durço; Vane,Matheus Fachini; Andrade,Rafael Bicarato de; Domingues,Maria Aparecida; Carvalho,Lidia Raquel de; Santos,Daniela Carvalho dos

PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME). METHODS: Forty-two rabbits (2.5-4.5 Kg) were randomly allocated into seven groups of six animals each: SHAM- surgical treatment alone; Bolus Control Group - 3 mL-intravenous (IV) bolus of saline; Continuous Infusion Control Group - 3 mL- I...

Date: 2013   |   Origin: Oasisbr

Aspectos clínicos, histológicos e de microscopia eletrônica dos granulomas de i...

Martins,Regina Helena Garcia; Dias,Norimar Hernandes; Santos,Daniela Carvalho dos; Fabro,Alexandre Todorovic; Braz,José Reinaldo Cerqueira

Granulomas são lesões bilaterais e pediculadas das apófises vocais. Etiologias: intubação, refluxo, traumatismos, fonotraumatismo e idiopática. OBJETIVO: Analisar aspectos clínicos e morfológicos dos granulomas de intubação. MATERIAL E MÉTODOS: Estudo retrospectivo dos pacientes submetidos à microcirurgia por granulomas de intubação, atendidos na Instituição onde foi realizado, a partir de 2002. Analisaram-se: ...

Date: 2009   |   Origin: Oasisbr

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