4 documents found, page 1 of 1
α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced...
Lima,R.P. de; Nunes,P.I.G.; Viana,A.F.S.C.; Oliveira,F.T.B. de; Silva,R.A.C.; Alves,A.P.N.N.; Viana,D.A.; Fonseca,S.G.C.; Carvalho,A.A.; Chaves,M.H.Nonalcoholic fatty liver disease (NAFLD), characterized by hepatosteatosis and steatohepatitis, is intrinsically related to obesity. Our previous study reported on the anti-obese activity of α,β-amyrin (AMY), a pentacyclic triterpene isolated from Protium heptaphyllum. This study investigated its ability to prevent fatty liver and the underlying mechanism using the mouse model of NAFLD. NAFLD was induced in mal...
Acute blockade of endogenous melatonin by Luzindole, with or without peripheral...
Matos,R.S.; Oriá,R.B.; Bruin,P.F.C.; Pinto,D.V.; Viana,A.F.S.C.; Santos,F.A.; Duarte,A.S.G.; Bruin,V.M.S.This study investigated the acute blockade of endogenous melatonin (MLT) using Luzindole with or without systemic lipopolysaccharide (LPS) challenge and evaluated changes in inflammatory and oxidative stress markers in the mouse jejunum. Luzindole is an MT1/MT2 MLT receptor antagonist. Both receptors occur in the small intestine. Swiss mice were treated with either saline (0.35 mg/kg, ip), Luzindole (0.35 mg/kg...
Ferulic acid lowers body weight and visceral fat accumulation via modulation of...
de Melo,T.S.; Lima,P.R.; Carvalho,K.M.M.B.; Fontenele,T.M.; Solon,F.R.N.; Tomé,A.R.; de Lemos,T.L.G.; da Cruz Fonseca,S.G.; Santos,F.A.; Rao,V.S.Previous studies have reported on the glucose and lipid-lowering effects of ferulic acid (FA) but its anti-obesity potential has not yet been firmly established. This study investigated the possible anti-obesitogenic effects of FA in mice fed a high-fat diet (HFD) for 15 weeks. To assess the antiobesity potential of FA, 32 male Swiss mice, weighing 20–25 g (n=6–8 per group) were fed a normal diet (ND) or HFD, t...
Níveis de fósforo disponível em dietas para suínos dos 15 aos 30kg
Viana,J.M.; Brustolini,P.C.; Silva,F.C.O.; Saraiva,A.; Donzele,J.L.; Oliveira,R.F.M.; Ferreira,A.S.; Santos,F.A.; Paula,E.Avaliou-se a suplementação de dietas com fósforo disponível (Pd) para suínos selecionados para deposição de carne, utilizando-se 100 leitões com média de peso inicial de 15,03±0,33kg, distribuídos em delineamento de blocos ao acaso, com cinco tratamentos, cinco repetições e quatro animais por unidade experimental. Os tratamentos foram dieta basal sem suplementação de fosfato bicálcico e outras quatro dietas obt...