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CD4+ recent thymic emigrants are infected by HIV in vivo, implication for patho...

Fabre-Mersseman, Véronique; Dutrieux, Jacques; Louise, Anne; Rozlan, Sandra; Lamine, Aurélia; Parker, Raphaëlle; Rancez, Magali; Nunes-Cabaço, Helena

OBJECTIVE: The contribution of naive CD4+ T cells to the pool of HIV-infected cells remains poorly described. This study aimed at evaluating HIV infection in naive T-cell subsets in viremic and HAART-treated patients, together with various parameters implicated in naive T-cell homeostasis, in order to better understand infection in these subsets. DESIGN AND METHODS: HIV provirus was quantified in various FACS-s...

Date: 2011   |   Origin: Repositório da Universidade de Lisboa
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