2 documents found, page 1 of 1
Synthesis, Antitubercular and Leishmanicidal Evaluation of Resveratrol Analogues
Coimbra,Elaine S.; Santos,Juliana A.; Lima,Larissa L.; Machado,Patrícia A.; Campos,Débora L.; Pavan,Fernando R.; Silva,Adilson D.In this paper we continue our efforts in the search for new Schiff bases as resveratrol analogues as promising antitubercular and antileishmanial agents. Compounds were evaluated in vitro against Mycobacterium tuberculosis and Leishmania species. Compounds showed varying activity against promastigotes of all Leishmania species tested (concentration leading to reduction of 50% of parasite growth-IC50 values rang...
Isolation of a lipase-producing Trichosporon spp and enzyme extraction by two-p...
Santos,Juliana A.; Amaral,Marcel C.O.; Araújo,Thiago A.S.; Fernandes,Késsia G.C.; Chaves,Adilson C.; Morais,Márcia M.C.A lipase-producing yeast strain isolated from crude cheese and identified as Trichosporon spp produced 7.3 U/mL (59.3 U/µg) after 72h of cultivation. Lipase showed optimum activity at pH 7.0-8.0 and 45-50ºC. Extraction by the two-phase aqueous system (PEG-phosphate salts) showed an elevated recuperation (99.8%) of enzymatic activity in the PEG phase.