Deoxynivalenol (DON), an enteropathogenic mycotoxin produced by Fusarium species, is usually associated with adverse health outcomes such as gastrointestinal diseases and immunotoxicity. To estimate DON exposure of the Portuguese population at national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering the inputs of the food consumption data generated within the ...
Background: Early-life exposure occurs during gestation through transfer of toxic substances present in the maternal diet to the fetus and later on, during lactation, through the breast milk. Food chemical contaminants as mycotoxins are well known carcinogenic, nephrotoxic, hepatotoxic and immunosuppressive compounds. Recent human biomonitoring data revealed that Portuguese population is exposed to mycotoxins. ...
Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. In order to overcome this lack of data, the present study concerned the analysis ...
Mycotoxins constitute a relevant group of food contaminants with associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring (HBM) studies have been globally developed to assess the exposure to mycotoxins at individual level. This study aimed to present data for mycotoxins’ urinary biomarkers within a human ...
Recent studies under MYCOMIX project reported that Portuguese children until 3 years old are exposed to multiple mycotoxins through food consumption, constituting a potential health threat. Aflatoxins (carcinogenic toxins) represented the main risk contributors and deoxynivalenol (a non-carcinogenic toxin associated with immunological and gastrointestinal toxic effects) showed the highest daily intake of the st...
Mycotoxins are secondary metabolites produced by fungi that occurs widely in food commodities, and are known to potentially cause toxicity and carcinogenic outcomes to humans. Therefore, it is crucial to assess the population exposure to mycotoxins. Biomarker-driven research appeared as a promising method to assess the mycotoxin exposure in humans. To date, in Portugal, there is a lack of human studies to asses...