3 documents found, page 1 of 1
Evaluation of peptidylarginine deiminase 4 and PADI4 polymorphisms in sepsis-in...
Costa,Nara Aline; Polegato,Bertha Furlan; Pereira,Amanda Gomes; Paiva,Sérgio Alberto Rupp de; Gut,Ana Lúcia; Balbi,André Luís; Ponce,DanielaSUMMARY BACKGROUND: The aim of this study is to evaluate the peptidylarginine deiminase 4 (PAD 4) concentration and PADI4 polymorphisms as predictors of acute kidney injury (AKI) development, the need for renal replacement therapy (RRT), and mortality in patients with septic shock. METHODS: We included all individuals aged ≥ 18 years, with a diagnosis of septic shock at ICU admission. Blood samples were taken w...
Remodelação miocárdica após infarto agudo do miocárdio experimental em ratos: e...
Epifanio,Hindalis Ballesteros; Zornoff,Leonardo Antonio Mamede; Matsubara,Beatriz Bojikian; Paiva,Sergio Alberto Rupp de; Inoue,Roberto Minoru TaniOBJETIVO: Verificar a ação do lisinopril e do losartan sobre a remodelação miocárdica no infarto experimental em ratos. MÉTODOS: Ratos machos Wistar foram submetidos a infarto e tratados com lisinopril 20 mg/kg/dia (LIS, n=13) ou losartan 20 mg/kg/dia (LOS, n=11), ou mantidos sem tratamento (NT, n=11), por três meses e os resultados comparados com grupo controle (CONT, n=11) de ratos sem infarto. Após a eutanás...
Behavior of cardiac variables in animals exposed to cigarette smoke
Paiva,Sergio Alberto Rupp de; Zornoff,Leonardo Antonio Mamede; Okoshi,Marina Politi; Okoshi,Katashi; Cicogna,Antonio Carlos; Campana,Alvaro OscarOBJECTIVE: To assess the behavior of cardiac variables in animals exposed to cigarette smoke. METHODS: Two groups of Wistar rats were studied as follows: control group (C), comprising 28 animals; and smoking group (S), comprising 23 animals exposed to cigarette smoke for 30 days. Left ventricular cardiac function was assessed in vivo with transthoracic echocardiography, and myocardial performance was analyzed i...