11 documents found, page 1 of 2

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Echocardiographic screening of valvular heart disease in granulomatosis with po...

Santos De Sousa, Catarina Isabel

Systemic vasculitides are rare autoimmune-mediated disorders affecting various organs. Their clinical presentation is usually heterogeneous, with a long and difficult period until a diagnosis is finally established. They are classified according to the type of affected vessels, pathogenesis, demographics and clinical characteristics. Granulomatosis with polyangiitis (GPA), formerly Wegener’s granulomatosis, is ...


Infective endocarditis risk in patients with bicuspid aortic valve: systematic ...

Couto Pereira, Sara Cristina; Abrantes, Ana; António, Pedro Silverio; Morais, Pedro; Santos De Sousa, Catarina Isabel; David, Cláudio; Pinto, Fausto J.

Background: Antibiotic prophylaxis in bicuspid aortic valve patients is currently a matter of debate. Although it is no longer recommended by international guidelines, some studies indicate a high risk of infective endocarditis. We aim to evaluate the risk of native valve infective endocarditis in bicuspid aortic valve patients and compare to individuals with tricuspid aortic valve. Methods: Study search of lon...


Management of arterial hypertension: challenges and opportunities

Valente Silva, Beatriz; Santos De Sousa, Catarina Isabel; Caldeira, Daniel; Abreu, Ana; Pinto, Fausto J.

Systemic arterial hypertension (HTN) is still the leading cause of disability‐adjusted life‐years and death globally. It affects over one billion adults globally and 10% of the global healthcare spending is directly related to HTN and its complications. The progress in HTN awareness, treatment, and control rates has plateaued or even deteriorated in the last 20 years, particularly in low‐ and middle‐income coun...


The epidemiology of infective endocarditis in Portugal : Prevalence, incidence,...

Santos De Sousa, Catarina Isabel

Infective endocarditis (IE) is an infrequent clinical condition with a challenging diagnosis and management. An infection of the endocardium, prosthetic or intracardiac devices predominantly caused by bacteria occurs, with a multisystemic involvement and heterogeneous clinical presentation. A long hospitalization course is usually mandatory. Despite several advances in the fields of medical imaging, microbiolog...


In-hospital outcomes of infective endocarditis from 1978 to 2015: analysis thro...

Resende, Plinio; Fortes, Claudio Querido; Nascimento, Emilia Matos do; Santos De Sousa, Catarina Isabel; Querido Fortes, Natalia Rodrigues

Background: Early identification of patients with infective endocarditis (IE) at higher risk for in-hospital mortality is essential to guide management and improve prognosis. Methods: A retrospective analysis was conducted of a cohort of patients followed up from 1978 to 2015, classified according to the modified Duke criteria. Clinical parameters, echocardiographic data, and blood cultures were assessed. Techn...


Dapagliflozin post‐transcatheter aortic valve implantation: the need for furthe...

Santos De Sousa, Catarina Isabel; Pinto, Fausto J.

Após catorze décadas de evolução médica e tecnológica, a endocardite infeciosa continua a desafiar médicos no seu diagnóstico e manejo diário. O aumento da incidência, alterações demográficas (afetando pacientes mais idosos), microbiologia com taxas de infeção por Staphylococcus mais elevadas, com complicações graves ainda frequentes e uma mortalidade substancial tornam a endocardite uma doença muito complexa. ...


Infective endocarditis: still more challenges than convictions

Santos De Sousa, Catarina Isabel; Pinto, Fausto J.

After fourteen decades of medical and technological evolution, infective endocarditis continues to challenge physicians in its daily diagnosis and management. Its increasing incidence, demographic shifts (affecting older patients), microbiology with higher rates of Staphylococcus infection, still frequent serious complications and substantial mortality make endocarditis a very complex disease. Despite this, inn...


Infective endocarditis in Portugal: another piece added to the puzzle

Santos De Sousa, Catarina Isabel

The reported low incidence of infective endocarditis (IE) ranging between 3 and 10 per 100 000 people is probably underestimated, as a diagnosis is often challenging. A temporal increase has been documented in some European countries such as United Kingdom (UK), Germany or Denmark. Recently, an analysis on IE in the Portuguese population over the last decade identified a similar trend. An aging population, an i...


Qual o verdadeiro impacto da intervenção coronária percutânea on‐site? Análise ...

Vicente Miranda, Hugo; Santos De Sousa, Catarina Isabel; Santos, Hélder; Almeida, Inês; Chin, Joana; Almeida, Samuel; Tavares, João

Introduction: In an era in which coronary heart disease is one of the leading causes of death worldwide, several studies report the persistence of obstacles to accessing revascularization, and percutaneous coronary intervention in particular, which may be associated with worse outcomes. Objectives: To compare cardiovascular outcomes in patients admitted to hospitals with and without on-site percutaneous coronar...


Insight into the epidemiology of infective endocarditis in Portugal : a contemp...

Santos De Sousa, Catarina Isabel; Nogueira, Paulo Jorge; Pinto, Fausto J.

Background Nationwide hospital admissions data series have contributed to a reliable assessment of the changing epidemiology of infective endocarditis, even though conclusions are not uniform. We sought to use a recent populational series to describe the temporal trends on the incidence of infective endocarditis, its clinical characteristics and outcome results, in Portugal. Methods A nationwide retrospective t...


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