3 documents found, page 1 of 1
Sensitivity of different DNA extraction methods and PCR to detect resistance in...
Sevilha-Santos, Lais; Aquino, Danielle Costa; Hans Neto, Günter; Costa, Fabiano José Queiroz; Sousa, Carlos Augusto Felipe de; Morelo, Elaine FariaIntroduction: Antimicrobial resistance in leprosy is an emerging problem, and the quantitative impact of low bacilloscopic indexes (BIs) on the sensitivity of molecular tests is unknown. We aimed to evaluate the sensitivity of gene sequencing for the detection of mutations related to antimicrobial resistance in Mycobacterium leprae in patients with low BIs using an analytical model. Methods: Patients with lepro...
Oxidonitrergic and antioxidant effects of a low molecular weight peptide fracti...
Graziane, Daniel; Ribeiro, J. V. V.; Cruz, V. S.; Gomes, R. M.; Araujo, E. G.; Santos Júnior, Agenor de Castro Moreira dos; Tomaz, H. C. M.About 3000 tons of beans are not used in human food due to hardening. Several studies on bean-derived bioactive peptides have shown potential to treat some diseases, including those relying on oxidative dysfunctions. We assessed the effects of peptides extracted from hardened bean Phaseolus vulgaris (PV) on reactive oxygen species (ROS) and nitric oxide (NO) production, cytotoxic and cytoprotective effects in e...
Proteômica de tripanosomatídeos : divisão celular de Trypanosoma cruzi e anális...
Santos Júnior, Agenor de Castro Moreira dosTese (doutorado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2018.; Os tripanosomatídeos compõem uma família de protozoários com flagelos únicos que inclui patógenos de invertebrados, vertebrados e plantas. Alguns desses protozoários causam importantes doenças humanas como é o caso do Trypanosoma cruzi, causador da doença de Chagas. Os tripanossomatídeos po...