4 documents found, page 1 of 1
Effectiveness of an immunohistochemical protocol for Leishmania detection in di...
Marques, Fernanda A; Soares, Rodrigo P; Almeida, Greg?rio G; Souza, Carolina Carvalho de; Melo, Maria Norma; Pinto, Sebasti?o AlvesUniversidade Federal de Minas Gerais. Instituto de Ci?ncias Biol?gicas. Departamento de Patologia Geral. Belo Horizonte, MG, Brazil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brazil.; Universidade Federal de Minas Gerais. Instituto de Ci?ncias Biol?gicas. Departamento de Patologia Geral. Belo Horizonte, MG, Brazil.; Universidade Federal de Minas Gerais. Instituto de Ci?ncias B...
A vaccine therapy for canine visceral leishmaniasis promoted significant improv...
Roatt, Bruno Mendes; Soares, Rodrigo Dian de Oliveira Aguiar; Reis, Levi Eduardo Soares; Cardoso, Jamille Mirelle de OliveiraHerein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of Leishmania braziliensis associated with MPL adjuvant (LBMPL vaccine) for visceral leishmaniasis (VL) in symptomatic dogs naturally infected by Leishmania infantum. Sixteen dogs received immunotherapy with MPL adjuvant (n = 6) or with a vaccine composed of antigens of L. braziliensis associated with M...
A potential link among antioxidant enzymes, histopathology, and trace elements ...
Souza, Carolina Carvalho de; Barreto, Tatiane Oliveira; Silva, Sydnei Magno da; Pinto, Aldair Junio Woyames; Figueiredo, Maria MartaCanine visceral leishmaniasis (CVL) is a severe and fatal systemic chronic inflammatory disease. We investigated the alterations in, and potential associations among, antioxidant enzymes, trace elements and histopathology in CVL. Blood and tissue levels of Cu-Zn superoxide dismutase, catalase and glutathione peroxidase were measured in mixed-breed dogs naturally infected with Leishmania infantum chagasi, sympto...
Leishmania metacyclogenesis is promoted in the absence of purines.
Serafim, Tiago Donatelli; Figueiredo, Amanda Braga de; Costa, Pedro Augusto Carvalho; Silva, Eduardo de Almeida Marques da; Gonçalves, RicardoLeishmania parasites, the causative agent of leishmaniasis, are transmitted through the bite of an infected sand fly. Leishmania parasites present two basic forms known as promastigote and amastigote which, respectively, parasitizes the vector and the mammalian hosts. Infection of the vertebrate host is dependent on the development, in the vector, of metacyclic promastigotes, however, little is known about the ...