11 documents found, page 1 of 2
Cytocompatibility and Synergy of EGCG and Cationic Peptides Against Bacteria Re...
Caiaffa, Karina Sampaio [UNESP]; dos Santos, Vanessa Rodrigues [UNESP]; Abuna, Gabriel Flores; Santos-Filho, Norival Alves [UNESP]Made available in DSpace on 2022-04-29T08:31:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; This study evaluated the cytocompatibility and antimicrobial/antibiofilm effects of epigallocatechin-3-gallate (EGCG) associated with peptide LL-37 and its analogue KR-12-a5 against oral pathogens. The effect of the compounds on metabolism of fibroblasts was evaluated by methyltetrazolium assays. Antimi...
Effect of C-terminal and N-terminal dimerization and alanine scanning on antiba...
Santos-Filho, Norival Alves [UNESP]; Righetto, Gabriela Marinho; Pereira, Marina Rodrigues [UNESP]; Piccoli, Julia Pinto [UNESP]Made available in DSpace on 2022-05-01T09:00:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The peptide (p-BthTX-I)2 [(KKYRYHLKPFCKK)2] and its analog des-Lys12,Lys13-(p-BthTX-I)2 [(KKYRYHLKPFC)2] showed activity against bacteria and potential specificity against...
Haematological, biochemical and immunological biomarkers, antibacterial activit...
de Sousa, Elielma Lima [UNESP]; Assane, Inácio Mateus [UNESP]; Santos-Filho, Norival Alves [UNESP]; Cilli, Eduardo Maffud [UNESP]Made available in DSpace on 2021-06-25T10:45:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-25; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Among the antimicrobial peptides (AMPs), which act as natural antibiotics in preventing the colonization of pathogens, LL-37 is noteworthy. It is a human cathelicidin characterized as a broad-spectrum antibiotic, with chemotactic and immunom...
Understanding the mechanism of action of peptide (p-BthTX-I)2 derived from C-te...
Santos-Filho, Norival Alves [UNESP]; de Freitas, Laura Marise [UNESP]; Santos, Claudia Tavares dos [UNESP]; Piccoli, Julia Pinto [UNESP]Made available in DSpace on 2021-06-25T10:57:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Based on the antimicrobial activity of bothropstoxin-I (BthTX-I) and on the premise that a C-terminal ...
Baltetin: a new C-type lectin-like isolated from Bothrops alternatus snake veno...
Pereira, Déborah Fernanda da Cunha; Matias Ribeiro, Mariana Santos; de Sousa Simamoto, Bruna Barbosa; Dias, Edigar Henrique VazMade available in DSpace on 2021-06-25T10:59:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-30; C-type lectin-like proteins found in snake venom, known as snaclecs, have important effects on hemostasis through targeting membrane receptors, coagulation factors and other hemostatic proteins. Here, we present the isolation and functional characterization of a snaclec isolated from Bothrops alternatus...
STUDY ON THE MECHANISM OF ANTIBACTERIAL ACTION OF THE PEPTIDES P-BTHTX-I AND IT...
Santos-Filho, Norival Alves [UNESP]; Freitas, Laura Marise de [UNESP]; Santos, Claudia Tavares dos [UNESP]; Piccoli, Julia Pinto [UNESP]Made available in DSpace on 2020-12-12T00:26:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-03-05; Univ Estadual Paulista Unesp, Inst Quim, Araraquara, SP, Brazil; Univ Estadual Paulista Unesp, Fac Ciencias Farmaceut, Araraquara, SP, Brazil; Univ Estadual Paulista Unesp, Inst Quim, Araraquara, SP, Brazil; Univ Estadual Paulista Unesp, Fac Ciencias Farmaceut, Araraquara, SP, Brazil
In vitro tracking of phospholipase A(2) from snake venom conjugated with magic-...
Dias, Edigar H. V.; Pereira, Deborah F. C.; Sousa, Bruna B. de [UNESP]; Matias, Mariana S.; Queiroz, Mayara R. de; Santiago, Fernanda M.Made available in DSpace on 2019-10-04T11:56:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Ministerio de Ciencias e Tecnologia (MCT) of Brazil; Phospholipases A(2) represent a family of enz...
Antimicrobial Photodynamic therapy enhanced by the peptide aurein
De Freitas, Laura Marise [UNESP]; Lorenzón, Esteban Nicolás; Santos-Filho, Norival Alves [UNESP]; Zago, Lucas Henrique De Paula [UNESP]Made available in DSpace on 2018-12-11T17:36:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; In the past few years, the World Health Organization has been warning that the post-antibiotic era is an increasingly real threat. The rising and disseminated resistance to antibiotics made mandatory the search for new drugs and/or alternative therapies that are able to eliminate resistant microorganism...
LmrBPP9: A synthetic bradykinin-potentiating peptide from Lachesis muta rhombea...
Pinheiro-Junior, Ernesto Lopes; Boldrini-Franca, Johara; Pires de Campos Araujo, Luciana Mattoso; Santos-Filho, Norival Alves [UNESP]Made available in DSpace on 2018-11-29T09:28:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Bradykinin-potentiating peptides (BPPs) are an important group of toxins present in Lachesis muta rhombeata venom. They act directly at renin-angiotensin-aldosterone syste...
KR-12-a5 is a non-cytotoxic agent with potent antimicrobial effects against ora...
Caiaffa, Karina Sampaio [UNESP]; Massunari, Loiane [UNESP]; Danelon, Marcelle [UNESP]; Abuna, Gabriel Flores; Bedran, Telma Blanca Lombardo [UNESP]Made available in DSpace on 2018-12-11T17:15:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-26; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); This study evaluated the cytotoxicity and antimicrobial activity of analogs of cationic peptides against microorganisms associated with endodontic infections. L-929 fibroblasts were exposed to LL-37, KR-12-a5 and hBD-3–1CV and chlorhe...