3 documents found, page 1 of 1
Interaction study between vancomycin and liposomes containing natural compounds...
Cavalcanti, Isabella Macário Ferro; Menezes, Talita Gomes Calaça; Campos, Luís André de Almeida; Ferraz, Milena Sales; Maciel, Maria Amélia VieiraThe treatment of infections caused by resistant microorganisms is limited, and vancomycin (VAN) treatment failures for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are not uncommon, even when MRSA clinical isolates are susceptible to VAN. Thus, this study proposed the association of VAN with usnic acid and β-lapachone encapsulated into liposomes as a novel therapeutic option for infections caus...
Validation of a UV-spectrophotometric analytical method for determination of LP...
Ferraz, Rafaela Siqueira; Mendonça, Elisângela Afonso Moura; Silva, Jéssica Priscila Avelino; Cavalcanti, Isabella Macário FerroThe aim of this study was to develop and validate a UV spectrophotometric method for determination of LPSF/AC04 from inclusion complex and encapsulated into liposomes. The validation parameters were determined according to the International Conference on Harmonisation (ICH) and National Health Surveillance Agency (ANVISA) guidelines. LPSF/AC04 was determined at 250 nm in methanol by a UV spectrophotometric meth...
Desenvolvimento e validação de método analítico em CLAE-UV para a quantificação...
Velloso, Fabiana Toledo; Ferraz, Rafaela Siqueira; Lira, Ana Amélia Moreira; Santana, Davi Pereira de; Santos-Magalhães, Nereide StelaO ácido retinóico (AR) tem sido utilizado para o tratamento de acne severa, rugas, estrias e celulite, no entanto, provoca irritação na pele e sofre rápida degradação quando exposto à luz e ao calor. Métodos analíticos rápidos para quantificação do AR são, portanto, necessários para ensaios de cinética de liberação in vitro. Nesse contexto, o objetivo deste trabalho foi desenvolver e validar um método rápido e ...