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XRCC4 rs28360071 intronic variant is associated with increased risk for infant ...
Louzada-Neto,Orlando; Lopes,Bruno A.; Brisson,Gisele D.; Andrade,Francianne G.; Cezar,Ingrid S.; Santos-Rebouças,Cíntia B.; Albano,Rodolpho M.Abstract Early age acute leukemia (EAL) shows a high frequency of KMT2A-rearrangements (KMT2A-r). Previous investigations highlighted double-strand breaks arising from maternal exposure to xenobiotics during pregnancy as a risk factor for EAL and KMT2A-r. In this case-control study, we investigated the relationship between EAL and genetic variants of the nonhomologous end-joining (XRCC6 rs5751129, XRCC4 rs68693...
Date: 2020
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Origin: Oasisbr