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Radionuclide therapy: current status and prospects for internal dosimetry in in...

Sapienza, Marcelo Tatit; Willegaignon, José

The efficacy and toxicity of radionuclide therapy are believed to be directly related to the radiation doses received by target tissues; however, nuclear medicine therapy continues to be based primarily on the administration of empirical activities to patients and less frequently on the use of internal dosimetry for individual therapeutic planning. This review aimed to critically describe the techniques and cli...

Date: 2019   |   Origin: Oasisbr

Comparison of different quantification methods for 18F-fluorodeoxyglucose-posit...

Prando, Silvana; Carneiro, Camila de Godoi; Robilotta, Cecil Chow; Sapienza, Marcelo Tatit

OBJECTIVES: This study aimed to evaluate several methods to estimate glucose consumption in the male Wister rat brain as measured by PET. METHODS: Fourteen male Wistar normoglycemic rats were studied. The input function consisted of seventeen blood samples drawn manually from the femoral artery. Glucose uptake values were calculated using the input function resulting from the arterial blood samples and the tiss...

Date: 2019   |   Origin: Oasisbr




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