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Long COVID-19 fatigue and obstructive sleep apnea: is there a relation?

Pires, L.; Ribeiro, R.; Belchior, I.; Saraiva, C.; Fatal, T.; Guimarães, M. J.; Moniri, Armin; Drummond, M.

Fatigue has been reported as the most frequent long COVID-19 symptom. There is a physiological plausibility for relation be tween OSA and long-COVID-19 fatigue, by Intermittent nocturnal hypox emia, endothelial dysfunction, oxidative stress and low grade systemic inflammation. OSA activates the renin-angiotensin-aldosterone system (RAAS) and angiotensin-converting enzyme 2 (ACE2), which is the entry receptor fo...


Improving non-small-cell lung cancer survival through molecular characterizatio...

Fernandes, M. G. O.; Vilariça, A. S.; Fernandes, B.; Camacho, C.; Saraiva, C.; Estevinho, F.; Bastos, H. Novais e; Lopes, J. M.; Fidalgo, P.

The management of NSCLC remains challenging, and the integration of data from predictive biomarkers in routine clinical practice can contribute to an optimal, individualized patient approach, particularly given the rapid emergence of effective targeted therapies. When considering molecular biomarker testing, the choice of the biomarker panel, target population, testing approach, and turnaround time are key issu...


Endocrinology in Portugal - Census 2016. Board of the Portuguese College of End...

Guimarães, J.; Afonso, A.; Carvalho, D.; Marques, A.; Martins, T.; Mascarenhas, M.; Pereira, C.; Rodrigues, D.; Saraiva, C.; Cardoso, H.

INTRODUCTION: On September 2016, the Board of the College of Endocrinology and Nutrition of the Portuguese Medical Association carried out a national survey, about all Endocrinology, Diabetes and Metabolism Departments of the public hospitals included in the Portuguese National Health Service and a simplified version of this survey was sent to all endocrinologists working in Portugal and registered with the Por...


MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson’s disease

Saraiva, C.; Paiva, J.; Santos, T.; Ferreira, L.; Bernardino, L.

Preprint version; This work was supported by Foundation for Science and Technology (FCT), FEDER and COMPETE (FCOMP-01-0124-FEDER-041099), EXPL/BIM-MED/0822/2013, SFRH/BD/90365/2012, SFRH/BD/79526/2011, L’Oréal-UNESCO Portugal for Women in Science, EC (ERC project nº 307384, “Nanotrigger”) and co-funded by FEDER (QREN), through Programa Mais Centro under project CENTRO-07-ST24-FEDER-002008 and PEst-C/SAU/UI0709/...


Sustainable Production Programme in Setúbal Region (PROSSET) : preliminary resu...

Duarte, Ana Paula; Peneda, Maria Constança; Sousa Rocha, Cristina; Saraiva, C.; Catarino, Justina; Frazão, Rui; Marçal, M.; Trindade, Paula

ABSTRACT: In this paper the PROSSET Programme is described briefly and the preliminary results are presented. The Programme includes cleaner production (CP) demonstration projects developed in 10 companies located in the Setúbal Region and the testing of methodologies to promote the sustainability of the Programme. Both the involvement of local agents and the training and/or awareness of workers and locals were...

Date: 1999   |   Origin: Repositório do LNEG

Sustainable Production Programme in Setúbal Region (PROSSET) : preliminary resu...

Duarte, Ana Paula; Peneda, Maria Constança; Sousa Rocha, Cristina; Saraiva, C.; Catarino, Justina; Frazão, Rui; Marçal, M.; Trindade, Paula

ABSTRACT: In this paper the PROSSET Programme is described briefly and the preliminary results are presented. The Programme includes cleaner production (CP) demonstration projects developed in 10 companies located in the Setúbal Region and the testing of methodologies to promote the sustainability of the Programme. Both the involvement of local agents and the training and/or awareness of workers and locals were...

Date: 1999   |   Origin: Repositório do LNEG

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