Over the last two decades, the possibility of using RPCs in outdoors systems has increased considerably. Our group has participated in this effort by installing several systems and continues to work on their optimization, while simultaneously studying and developing new approaches that can use RPCs in outdoor applications. In particular, four detectors were deployed in the field at the Pierre Auger Observatory ...
Over the last two decades, the possibility of using RPCs in outdoors systems has increased considerably. Our group has participated in this effort having installed several systems and continues to work on their optimization, while simultaneously studying and developing new approaches that can to use of RPCs in outdoor applications. In particular, some detectors were deployed in the field at the Pierre Auger Obs...
The aim of this study was to evaluate the impact of high-pressure processing (HPP) on the long-term storage of chocolate fillings at room temperature, compared with conventional storage at lower temperatures. Dark chocolate fillings were treated at different pressure levels, holding times and stored at 20 °C for 12 months. Unprocessed batches were stored at 4 °C and at -12 °C. Moisture, water activity (aw), pH,...
Serra da Estrela protected designation of origin (PDO) cheese is manufactured with raw milk from Bordaleira and/or Churra Mondegueira da Serra da Estrela sheep breeds. Several socio-environmental shortcomings have reduced production capacity; hence, treatments that may contribute to its efficient transformation into cheese are welcome. High-pressure processing (HPP) milk pre-treatment may contribute to a cheese...
The LouMu team joins together specialists in particle detectors and in cosmic ray analyses, geophysicists and science communicators to muograph an underground gallery of an old mine, now open to visitors of a science museum. The muon telescope is made of Resistive Plate Chambers (RPCs) developed to operate stably and with low consumption at remote locations, and it has been tested in the Coimbra University, bef...
Objective: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. Methods: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...
A high-quality GSM model for Streptococcus pneumoniae R6 model strain (iDS372), comprising 372 genes and 529 reactions, was developed. The construction of this model involved performing a genome-wide reannotation to identify the metabolic capacity of the bacterium. A reaction representing the abstraction of the biomass composition was reconciled from several studies reported in the literature and previous model...
INTRODUCTION: Most mental disorders have a chronic evolution and therefore a certain amount of psychiatric readmissions are inevitable. Several studies indicate that over 25% of child and adolescent inpatients were readmitted within one year of discharge. Several risk factors for psychiatric readmissions have been reported in the literature, but the history of repeated readmissions is the most consistent risk f...
A conservação de bombons artesanais apresenta algumas dificuldades devido ao facto de serem usadas matérias-primas perecíveis, alterações físicas durante o processamento e também devido a fatores externos que tendem a reduzir o tempo de prateleira. Os fatores mais importantes que contribuem para o tempo de prateleira incluem propriedades físicas (ex. secagem, sugar bloom ou fat bloom), estabilidade microbiológi...