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Bioengineered surgical repair of a chronic oronasal fistula in a cat using auto...

Soares, Carla S.; Barros, Luís C.; Saraiva, Virgínia; Gomez-Florit, Manuel; Babo, Pedro Miguel Sousa; Dias, Isabel R.; Reis, R. L.; Carvalho, Pedro P.

Clinical summary: A tissue engineering approach was used to aid the surgical repair of a chronic oronasal fistula (ONF) in a 13-year-old cat. A three-dimensional (3D) printed mesh, tailored to the size and shape of the ONF, was created to support a soft tissue flap used to close the defect; and also to provide a matrix for mesenchymal stromal cells present in bone marrow aspirate and bioactive cytokines and gro...


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