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Mean platelet volume predicts restenosis after carotid endarterectomy

Pereira-Neves, António; Saramago, Sean; Duarte-Gamas, Luís; Domingues-Monteiro, Diogo; Fragão-Marques, Mariana; Marques-Vieira, Mário; Andrade, José P.

Background: Carotid restenosis following carotid endarterectomy (CEA) has a cumulative risk at 5-years up to 32%, which may impact the well-being of patients following CEA. Haematological parameters in the standard complete blood cell count (CBC) are emerging as potential biomarkers, but their application in CEA is scarce. The primary aim of this study was to investigate haematological markers for restenosis fo...


Tuberculosis Vaccines: an update of recent and ongoing clinical trials

Saramago, Sean; Magalhães, Joana; Pinheiro, Marina

TB remains a global health challenge and, until now, only one licensed vaccine (the BCG vaccine) is available. The main goal of this work is to assess the progress in the development of new TB vaccines and highlight the research in nanovaccines. A review was conducted using a methodology with the appropriate keywords and inclusion and exclusion criteria. The search revealed 37 clinical trials that were further ...


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