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Treatment package time in high-risk oral cavity squamous cell carcinoma

Ferreira, Pedro; Esteves, Susana; Vilares, Miguel; Montalvão, Pedro; Rito, Miguel; Magno, Sara; Sargento, Isabel; Colaço, Raul; Netto, Eduardo

Background: The gold-standard of treatment for oral cavity squamous cell carcinoma (OCSCC) is surgery and adjuvant chemoradiotherapy (CRT) in the sub-group of high-risk patients. In this group of patients, treatment time is an important factor in clinical outcomes. We aim to study the influence of the treatment package time (TPT). Materials and methods: We conducted a retrospective study of patients with high-r...


Secundary Diabetes Mellitus, the tip of the iceberg: a report of two clinical c...

Paixão Duarte, Fernanda; Reis, Dinis; Barão, Pedro; Sargento, Isabel; Silva, Salete; Dutschmann, Luís

We describe two rare cases of secondary Diabetes Mellitus associated with a GH-secreting pituitary macroadenoma and to a unilateral cortisol-secreting adrenal tumour. The patients were admitted in the emergency room, before the endocrine diagnosis had been made, because of acute complications associated with diabetes. The clinical presentation of the first patient (Acromegaly) was serious hyperglycaemia and an ...


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