3 documents found, page 1 of 1
Septic arthritis: immunopathogenesis, experimental models and therapy
Colavite,Priscila Maria; Sartori,AlexandrinaSeptic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of thera...
Experimental infections with Paracoccidioides brasiliensis obtained from armadi...
Nishikaku,Angela Satie; Peraçoli,Maria Terezinha S.; Bagagli,Eduardo; Sugizaki,Maria Fátima; Sartori,AlexandrinaParacoccidioides brasiliensis causes paracoccidioidomycosis (PCM) that is one of the most prevalent systemic human mycoses in Latin America. Armadillos show a high incidence of PCM infection and could, therefore, be a natural reservoir for this fungus. In this study were compared the virulence profiles of isolates obtained from nine-banded armadillos (Dasypus novemcinctus) (PbT1 and PbT4) and isolates from PCM ...
Experimental visceral leishmaniasis in high and low antibody - producer mice (s...
Fechio,Cristiane Jellmayer; Soares,Angela Maria Victoriano de Campos; Oliveira,Silvio Luís de; Sartori,AlexandrinaLeishmaniasis is a typical parasite infection whose protective immunity depends on macrophage activation. Susceptibility to Leishmania donovani infection was compared in H (high antibody responder) and L (low antibody responder) mice from selection IV-A. H mice infected intravenously with 10(7) amastigotes of L. donovani were more susceptible to infection than their L counterparts. This higher susceptibility wa...