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Alkaline phosphatase dual-binding sites for collagen dictate cell migration and...

Susana Guerreiro; Unger, RE; Cerqueira, NMFSA; Sartoris, A; Martins, MJ; Barbosa, MA; Soares, R; Granja, PL; Kirkpatrick, CJ

Interactions between cell types, growth factors, and extracellular matrix components involved in angiogenesis are crucial for new vessel formation leading to tissue regeneration. This study investigated whether cocultures of fibroblasts and endothelial cells (ECs; from macro- or microvasculature) play a role in the formation of microvessel-like structures by ECs, as well as modulate fibroblast differentiation a...


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