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Aspirin but not statins is inversely related to gastric cancer with a duration–...

Pastorino, R; Pires Marafon, D; Sassano, M; Hoxhaj, I; Pelucchi, C; Liao, LM; Rabkin, CS; Sinha, R; Lunet, N; Morais, S; Zaridze, D; Maximovich, D

Background: Aspirin and statins have been suggested to have potential chemopreventive effects against gastric cancer (GC), although the results of previous studies have been inconsistent. This study therefore aimed to investigate the association between the use of aspirin and statins and GC. Methods: A pooled analysis of seven case-control studies within the Stomach Cancer Pooling Project, including 3220 cases ...


Dietary intake of vitamin C and gastric cancer: a pooled analysis within the St...

Sassano, M; Seyyedsalehi, MS; Collatuzzo, G; Pelucchi, C; Bonzi, R; Ferraroni, M; Palli, D; Yu, G-P; Zhang, Z-F; López-Carrillo, L; Lunet, N; Morais, S

Background: Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not consider intake of fruit and vegetables. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project, a consortium of epidemiological studies on GC. Methods: Fourteen case–control studies were included in the analysis (5362 cases, 11,497 controls...


Intake of Proton-Pump Inhibitors and Gastric Cancer within the Stomach Cancer P...

Sassano, M; Mariani, M; Pelucchi, C; Lunet, N; Morais, S; Martín, V; Moreno, V; Curado, MP; Dias-Neto, E; Leja, M; Gasenko, E; La Vecchia, C; Boccia, S

Background: A potential association between proton-pump inhibitors (PPI) and gastric cancer remains undefined. Thus, we aimed to evaluate such association within the Stomach cancer Methods: Data from five case-control studies of the StoP Project were included (1,889 cases and 6,517 controls). We assessed the impact of different exposure definitions, specifically any reported use of PPIs and exposure definitions...


Chronic metformin intake and gastric cancer: A pooled analysis within the Stoma...

Sassano, M; Mariani, M; Pelucchi, C; Vicente, M; Pinto-Carbó, M; Lunet, N; Morais, S; La Vecchia, C; Pastorino, R; Boccia, S

Introduction: The association between chronic use of metformin and risk of gastric cancer (GC) has been investigated with contradicting results. We aimed to study the association between chronic use of metformin and GC by using data from the Stomach cancer Pooling (StoP) Project, an epidemiological consortium of case-control studies on GC. Methods: Data from three studies of the StoP Project with available info...


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