4 documents found, page 1 of 1
Viral encephalitis: a practical review on diagnostic approach and treatment
Costa,Bruna Klein da; Sato,Douglas KazutoshiAbstract Objectives To review the diagnostic criteria for encephalitis and encephalopathy of presumed infectious etiology, as well as the diagnostic workup for viral encephalitis and its treatment approaches. The authors also intended to summarize relevant information on specific viruses frequently found in Brazil. Source of data Literature search on Pubmed/MEDLINE using the following keywords: “viral”, “enceph...
Brazilian Consensus for the Treatment of Multiple Sclerosis: Brazilian Academy ...
Marques,Vanessa Daccach; Passos,Giordani Rodrigues dos; Mendes,Maria Fernanda; Callegaro,Dagoberto; Lana-Peixoto,Marco AurélioABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice and management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from the Brazilian Committee on Treatment and Research in Multiple Sclerosis and the Neuroimmunology Scientific Department of the Brazilian Academy of Neurolo...
MOG-IgG associated optic neuritis is not multiple sclerosis
Costa,Bruna Klein da; Passos,Giordani Rodrigues dos; Becker,Jefferson; Sato,Douglas KazutoshiABSTRACT Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON patients with multiple sclerosis (MS) patients presenting with ON. Methods and results: Among the total of 38 patients with optic neuropathies, six patients with isolated ON were MOG-IgG ...
Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definiti...
Sato,Douglas Kazutoshi; Callegaro,Dagoberto; Lana-Peixoto,Marco Aurélio; Nakashima,Ichiro; Fujihara,KazuoNeuromyelitis optica spectrum disorders (NMOSD) are characterized by severe optic neuritis and/or longitudinally extensive transverse myelitis, and some brain lesions are also unique to NMOSD. Serum autoantibodies against aquaporin-4 (AQP4) are detected in most cases of NMOSD. However, some patients with NMOSD remain seronegative despite repetitive testing during attacks with highly sensitive cell-based assays....