2 documents found, page 1 of 1
Sort by
Issue Date
Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethy...
Clemente, A; Domingos, A; Grancho, AP; Iley, J; Moreira, R; Neres, J; Palma, N; Santana, AB; Valente, EA series of N-acyloxymethyl- and N-aminocarbonyloxymethyl derivatives of 2-azetidinones. 3, with different substituent patterns at the beta -lactam C-3 and C-4 positions, were designed as potential mechanism-based inhibitors for human leukocyte elastase and found to exhibit inhibitory potency and selectivity for the enzyme, (C) 2001 Elsevier Science Ltd. All rights reserved.
Date: 2001
|
Origin: Repositório da Universidade de Lisboa
N-Acyloxymethyl-2-azetidinones as Human Leukocyte Elastase Inhibitors
Santana, AB; Valente, E; Neres, J; Moreira, R; Palma, N; Grancho, AP; Domingos, A; Clemente, A; Iley, J
Date: 2000
|
Origin: Repositório da Universidade de Lisboa