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A globally applicable PCR-based detection and discrimination of BK and JC polyo...

Souza, Leandro Magalhães de; Savassi-Ribas, Flávia; Almeida, Stephanie G. S. de; Silva, Rubens Nei N. da; Baez, Camila F.; Zalis, Mariano Gustavo

BKV and JCV belong to the Polyomaviridae family and are opportunistic agents associated with complications in immunocompromised individuals. Although a single screening assay for both viruses would be convenient, the diversity of BKV and JCV serotypes and genotypes is a methodological challenge. In this paper, we developed a PCR method able to detect and segregate BKV and JCV, despite these genetic discrepancie...

Date: 2018   |   Origin: Oasisbr

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