Made available in DSpace on 2019-09-12T16:56:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2016; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Subantimicrobial dose doxycycline (SDD) has been used as an adjunct in periodontal treatment because of its matrix metalloproteinase inhibition properties. Although the benefits of SDD therapy, such as improvement in the paramet...