2 documents found, page 1 of 1
Can the free/total psa ratio predict undetected intraductal carcinoma and cribr...
Bernardino, RM; Yin, LB; Lajkosz, K; Cockburn, JG; Wettstein, MS; Woon, D; Nguyen, DD; Sayyid, R; Leão, R; van der Kwast, T; Fleshner, NBackground: Intraductal carcinoma (IDC) and cribriform pattern (Crib) of prostate cancer are recognised as independent prognosticators of poor outcome, both in prostate biopsies and radical prostatectomy (RP) specimens. Objective: This study aimed to determine the predictive value of Free-to-total PSA ratio (FPSAR) in identifying missed IDC/Crib at the time of biopsy as compared to the final surgical specimen. ...
Profiling of urinary extracellular vesicle protein signatures from patients wit...
Bernardino, R; Carvalho, AS; Hall, MJ; Alves, L; Leão, R; Sayyid, R; Pereira, H; Beck, HC; Campos-Pinheiro, L; Henrique, R; Fleshner, N; Matthiesen, RPrognostic tests and treatment approaches for optimized clinical care of prostatic neoplasms are an unmet need. Prostate cancer (PCa) and derived extracellular vesicles (EVs) proteome changes occur during initiation and progression of the disease. PCa tissue proteome has been previously characterized, but screening of tissue samples constitutes an invasive procedure. Consequently, we focused this study on liqui...