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S100, CD68, and MHC class II molecule expression in cervical high- and low-grad...

Cassandri,Fernanda; Tozetti,Inês Aparecida; Fernandes,Carlos Eurico dos Santos; Almeida,Flávia Gatto de; Falcão,Gustavo Ribeiro

INTRODUCTION: Some human papillomavirus (HPV) types are involved in malignant processes in the cervical epithelium, with 99% of cases attributed to oncogenic HPV infection. This study aimed to detect S100, CD68, and major histocompatibility complex class II (MHC-II) molecules in cervical uterine epithelial samples in patients with high- and low-grade lesions induced by HPV. METHODS: Fifty-eight samples from pat...

Data: 2012   |   Origem: Oasisbr

Linfócitos CD4, CD8 e células NK no estroma da cérvice uterina de mulheres infe...

Alves,Daniella Borges; Tozetti,Inês Aparecida; Gatto,Flávia Almeida; Cassandri,Fernanda; Ferreira,Alda Maria Teixeira

INTRODUÇÃO: A resposta imune pode ser um elemento chave para a progressão ou remissão da infecção pelo papilomavírus humano (HPV) no estroma da cérvice uterina. Este estudo objetivou quantificar no estroma cervical a presença de linfócitos T CD4, CD8 e células NK, por imunohistoquímica, em lesões de alto e baixo grau em pacientes infectadas por HPV MÉTODOS: Utilizou-se 56 amostras de biópsia da estroma cervical...

Data: 2010   |   Origem: Oasisbr

Determination of HPV DNA viral load by hybrid capture assay and its association...

Tozetti,Inês Aparecida; Scapulatempo,Ilzia Doraci Lins; Levi,José Eduardo; Ferreira,Antonio Walter

OBJECTIVE: To compare the relation between HPV viral load by hybrid capture II test (HCII) and cytological findings. METHODS: Three hundred sixty-two reagent samples to HPV DNA by HCII had their viral loads classified in four categories and correlated to cytological results. RESULTS: Twenty-two samples (6.1%) were reagent only to low-risk oncogenic types (group A) and 340 (93.9%) were reagent to high-risk oncog...

Data: 2006   |   Origem: Oasisbr

Multiple types of human papillomavirus in cervical samples in women in Campo Gr...

Tozetti,Inês Aparecida; Scapulatempo,Ilzia Doraci Lins; Kawski,Vicky Liege; Ferreira,Antonio Walter; Levi,José Eduardo

We analyzed 87 cervical samples from Campo Grande, Mato Grosso do Sul, with a PGMY/GP+ nested PCR system. Positive samples were typed using E7 type-specific primer pairs for HPV 6/11, 16, 18, 45 and 66. Eighteen samples (22%) were infected with HPV6/11, 18 samples (22%) with HPV66, 13 samples (15.9%) with HPV45, 8 samples (9.8%) with HPV18 and 7 samples (8.5%) with HPV16. Seventeen samples (20.7%) were infected...

Data: 2006   |   Origem: Oasisbr

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