6 documents found, page 1 of 1
Cytotoxic activity of essential oil from Leaves of Myrcia splendens against A54...
Montalvão, Monalisa Martins; Felix, Franciel Batista; Propheta Dos Santos, Edmilson William; Santos, Jileno Ferreira; de Lucca Júnior, WaldecyBackground Plants of the Myrcia genus have been widely used in folk medicine to treat various diseases, including cancer. Myrcia splendens species has a diverse chemical constitution, but the biological activities of its essential oil have not been well investigated. In this study to out the chemistry characterization of essential oil (EO) from the leaves of the species M. splendens from Brazil and evaluate cyt...
Anti‑leishmanial compounds from microbial metabolites: a promising source
Cunha, Ana F. S. da; Di C. Oliveira, Yvanna L.; Dolabella, Silvio S.; Scher, Ricardo; Souto, Eliana B.; Lopez, Jorge A.; Jain, SonaLeishmania is a complex disease caused by the protozoan parasites and transmitted by female phlebotomine sandfly. The disease affects some of the poorest people on earth with an estimated 700,000 to 1 million new cases annually. The current treatment for leishmaniasis is toxic, long, and limited, in view of the high resistance rate presented by the parasite, necessitating new perspectives for treatment. The dis...
Stearic acid, beeswax and carnauba wax as green raw materials for the loading o...
Galvão, Juliana G.; Santos, Raquel L.; Lira, Ana Amélia M.; Kaminski, Renata; Sarmento, Victor H.; Severino, Patricia; Dolabella, Silvio S.The use of lipid nanoparticles as drug delivery systems has been growing over recent decades. Their biodegradable and biocompatible profile, capacity to prevent chemical degradation of loaded drugs/actives and controlled release for several administration routes are some of their advantages. Lipid nanoparticles are of particular interest for the loading of lipophilic compounds, as happens with essential oils. S...
Evolutionary dynamics of the karyotype of the wasp Trypoxylon (Trypargilum) nit...
Pompolo, Silvia das Graças; Scher, RicardoCytogenetic analysis based on the distribution of C-bands showed two groups of karyotypes in a Trypoxylon nitidum population from the Rio Doce Park, State of Minas Gerais, Brazil. One of these groups, that was identical to a previously described karyotype (n = 15; 2n = 30), had a stable chromosome number and was rich in acrocentric chromosomes, whereas the other had a variable chromosome number (n = 12 to 14; 2...
Absorption levels and morphological features of fetal organs in wistar rats tre...
Bomfim, Kátia Michelle dos Anjos; Garcia, Carlos Alexandre Borges; Reis, Francisco Prado; Palmeira, José Arnaldo Vasconcelos; Scher, RicardoLead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this...
Investigation of protective effects of erythrina velutina extract against MMS i...
Dias, Antônio Santos; Silva, Déborah Soares Bispo Santos; Barboza, Benhur; Garcia, Anuska Conde Fagundes Soares; Oliveira, Betejane deErythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assess...