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Cymbopogon winterianus Essential Oil Attenuates Bleomycin-Induced Pulmonary Fib...

Tavares, Lívia A.; Rezende, Allan A.; Santos, Jymmys L.; Estevam, Charles S.; Silva, Ana M. O.; Schneider, Jaderson K.; Cunha, John L. S.

The essential oil of Cymbopogon winterianus (EOCW) is a natural product with antioxidant, anti-inflammatory, and antifibrotic properties. We studied the effect of EOCW in the progression of histological changes of pulmonary fibrosis (PF) in a rodent model. The oil was obtained by hydrodistillation and characterized using gas chromatography-mass spectrometry. Intratracheal instillation of bleomycin was performed...


Application of bar adsorptive microextraction for the determination of levels o...

Oliveira, Mariana N.; Gonçalves, Oriana C.; Ahmad, Samir M.; Schneider, Jaderson K.; Krause, Laiza C.; Neng, Nuno R.; Caramão, Elina B.

This work entailed the development, optimization, validation, and application of a novel analytical approach, using the bar adsorptive microextraction technique (BAμE), for the determination of the six most common tricyclic antidepressants (TCAs; amitriptyline, mianserin, trimipramine, imipramine, mirtazapine and dosulepin) in urine matrices. To achieve this goal, we employed, for the first time, new generation...


Cymbopogon winterianus essential oil attenuates bleomycin-induced pulmonary fib...

Tavares, Lívia A.; Rezende, Allan A.; Santos, Jymmys L.; Estevam, Charles S.; Silva, Ana M. O.; Schneider, Jaderson K.; Cunha, John L. S.

The essential oil of Cymbopogon winterianus (EOCW) is a natural product with antioxidant, anti-inflammatory, and antifibrotic properties. We studied the effect of EOCW in the progression of histological changes of pulmonary fibrosis (PF) in a rodent model. The oil was obtained by hydrodistillation and characterized using gas chromatographymass spectrometry. Intratracheal instillation of bleomycin was performed ...


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