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Platelet transfusions in adult ICU patients with thrombocytopenia

Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Chawla, Sanjay; Castro, Pedro; Povoa, Pedro

Funding Information: This study was funded by the Research Council of Rigshospitalet, the Ehrenreich's Foundation and the Dagmar Marshalls Foundation. None of the funders had any influence on the design, conduct or reporting of the study. Funding Information: The Department of Intensive Care at Rigshospitalet (CTA, AP, MHM, LR) has received funding for other research projects from Sygeforsikringen \u2018danmark...


Correction

Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Barratt-Due, Andreas; Chawla, Sanjay

When the article was published, the Result-section of the Abstract was given in a misleading wording. Instead of “Absence of acquired immune deficiency syndrome (AIDS), non-cancer-related immune deficiency, liver failure, male sex, septic shock, and bleeding at ICU admission were associated with the development of thrombocytopenia during ICU stay”. it should read “Non-AIDS-, non-cancer-related immune deficiency...


Thrombocytopenia and platelet transfusions in ICU patients

Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Barratt-Due, Andreas; Chawla, Sanjay

© 2023. The Author(s).; PURPOSE: Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on thrombocytopenia in ICU patients. METHODS: We conducted a prospective cohort study in adult ICU patients in 52 ICUs across 10 countries. We assessed frequencies of thrombocytopeni...


Septic shock 3.0 criteria application in severe COVID-19 patients

Cidade, José Pedro; Coelho, L M; Costa, Vasco; Morais, Rui; Moniz, Patrícia; Morais, Luís; Fidalgo, Pedro; Tralhão, António; Paulino, Carolina

©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.; BACKGROUND: Coronavirus disease 2019 (COVID-19) can be associated with life-threatening organ dysfunction due to septic shock, frequently requiring intensive care unit (ICU) admission, respiratory and vasopressor support. Therefore, clear clinical criteria are pivotal for early recognition of patients more likely to need pr...


Predictive value of D-dimer in the clinical outcome of severe COVID19 patients

Cidade, José P.; Coelho, Luís; Costa, Vasco; Morais, Rui; Moniz, Patrícia; Morais, Luís; Fidalgo, Pedro; Tralhão, António; Paulino, Carolina

BACKGROUND: COVID-19 is a new form of acute respiratory failure leading to multiorgan failure and ICU admission. Gathered evidence suggests that a 3-fold rise in D-dimer concentrations may be linked to poor prognosis and higher mortality. PURPOSE: To describe D-dimer admission profile in severe ICU COVID19 patients and its predictive role in outcomes and mortality. METHODS: Single-center retrospective cohort st...


Respiratory viruses in mechanically ventilated patients

Nazareth, Raquel; Chasqueira, Maria-Jesus; Rodrigues, Maria Lúcia; Paulino, Carolina; Conceição, Catarina; Lêdo, Lia; Segura, Úrsula; Santos, Madalena

BACKGROUND: Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with acute lower respiratory infections. The aim of this study was to evaluate the presence of respiratory viruses in the lower airways of individuals undergoing in...


What do we know about carbon monoxide poisoning and cardiac compromise?

Cardiga, Rosa; Proença, Margarida; Carvalho, Carolina; Costa, Luís; Botella, Arturo; Marques, Filipa; Paulino, Carolina; Carvalho, António

Carbon monoxide (CO) poisoning is one of the most common types of poisoning and the leading cause of death by poisoning worldwide. Cardiac injury caused by CO poisoning has been little described despite being a predictor of poor prognosis. We present the case of a healthy 24-year-old woman, admitted to our emergency room due to an episode of lipothymia without loss of consciousness. She reported holocranial hea...


Continuous Infusion of Piperacillin/Tazobactam in Septic Critically Ill Patient...

Gonçalves-Pereira, João; Oliveira, Bruno Serra; Janeiro, Sérgio; Estilita, Joana; Monteiro, Catarina; Salgueiro, Andrea; Vieira, Alfredo; Gouveia, Joao

The clinical efficacy of continuous infusion of piperacillin/tazobactam in critically ill patients with microbiologically documented infections is currently unknown. We conducted a retrospective multicenter cohort study in 7 Portuguese intensive care units (ICU). We included 569 critically ill adult patients with a documented infection and treated with piperacillin/tazobactam admitted to one of the participatin...


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