3 documents found, page 1 of 1
Correlation between cellular expression of complement regulatory proteins with ...
Viecceli,Daniela; Garcia,Mariana Pires; Schneider,Laiana; Alegretti,Ana Paula; Silva,Cristiano Kohler; Ribeiro,André Lucas; Brenol,Claiton ViegasAbstract Objectives: To correlate the basal expression of complement regulatory proteins (CRPs) CD55, CD59, CD35, and CD46 in B-lymphocytes from the peripheral blood of a cohort of 10 patients with rheumatoid arthritis (RA) initiating treatment with rituximab (RTX) with depletion and time repopulation of such cells. Methods: Ten patients with RA received two infusions of 1 g of RTX with an interval of 14 days. ...
The expression of CD56 antigen is associated with poor prognosis in patients wi...
Alegretti,Ana Paula; Bittar,Christina Matzenbacher; Bittencourt,Rosane; Piccoli,Amanda Kirchner; Schneider,Laiana; Silla,Lúcia Mariano; Bó,Suzane DalBACKGROUND: The expression of CD56 is considered a bad prognostic factor for overall survival, lower rates or short complete remission and extramedullary invasion but the results are controversial. The importance of validating new prognostic parameters in acute leukemias was the reason to investigate the CD56 expression in blast cells of patients with acute myeloid leukemia. METHODS: A cohort of 48 patients tre...
Expressão de proteínas reguladoras do complemento CD55, CD59, CD35 e CD46 na ar...
Piccoli,Amanda Kirchner; Alegretti,Ana Paula; Schneider,Laiana; Lora,Priscila Schmidt; Xavier,Ricardo MachadoA artrite reumatoide (AR) é uma doença autoimune, associada à sinovite poliarticular inflamatória, que acomete principalmente as articulações periféricas. Cerca de 1% da população mundial é afetada, sendo duas a três vezes mais prevalente em mulheres. Apresenta patogênese complexa e multifatorial. A sinóvia das articulações afetadas é infiltrada por linfócitos T e B, macrófagos e granulócitos. A sinóvia reumato...