2 documents found, page 1 of 1
Guidelines to Analyze Preclinical Studies Using Perinatal Derivatives
Pires, Ana Salomé; Bollini, Sveva; Botelho, Maria Filomena; Lang-Olip, Ingrid; Ponsaerts, Peter; Balbi, Carolina; Lange-Consiglio, AnnaThe last 18 years have brought an increasing interest in the therapeutic use of perinatal derivatives (PnD). Preclinical studies used to assess the potential of PnD therapy include a broad range of study designs. The COST SPRINT Action (CA17116) aims to provide systematic and comprehensive reviews of preclinical studies for the understanding of the therapeutic potential and mechanisms of PnD in diseases and inj...
Systematic review of the application of perinatal derivatives in animal models ...
Pichlsberger, Melanie; Jerman, Urška Dragin; Obradović, Hristina; Tratnjek, Larisa; Macedo, Ana Sofia; Mendes, Francisca; Fonte, Pedro; Hoegler, AnjaKnowledge of the beneficial effects of perinatal derivatives (PnD) in wound healing goes back to the early 1900s when the human fetal amniotic membrane served as a biological dressing to treat burns and skin ulcerations. Since the twenty-first century, isolated cells from perinatal tissues and their secretomes have gained increasing scientific interest, as they can be obtained non-invasively, have anti-inflamma...