2 documents found, page 1 of 1
Isolation, characterization, and differentiation of progenitor cells from human...
Santana, Magda M.; Chung, Kuei-Fang; Vukicevic, Vladimir; Salgado, Joana Rosmaninho; Kanczkowski, Waldemar; Cortez, Vera; Hackmann, KlausChromaffin cells, sympathetic neurons of the dorsal ganglia, and the intermediate small intensely fluorescent cells derive from a common neural crest progenitor cell. Contrary to the closely related sympathetic nervous system, within the adult adrenal medulla a subpopulation of undifferentiated progenitor cells persists, and recently, we established a method to isolate and differentiate these progenitor cells f...
DNA copy number profiles of gastric cancer precursor lesions
Buffart, Tineke; Carvalho, Beatriz; Mons, Thomas; Reis, R. M.; Moutinho, Cátia; Silva, Paula; Grieken, Nicole C. T. van; Vieth, Michael; Stolte, ManfredChromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still obscure. In the present study, we set out to study whether two morphologically distinct categories of gastric cancer precursor lesions, i.e. intestinal-type and pyloric gland adenomas, would carry different patterns of DNA copy number changes...