3 documents found, page 1 of 1
Investigation of oral and general health status and IL-1β gene polymorphism as ...
Curra,Marina; Baldin,Julianna Joanna Carvalho Moraes de Campos; Martins,Marco Antonio Trevizani; Schuch,Lauren FrenzelAbstract: The aim of the present study was to analyze the relationship of OM with possible risk factors such as oral health condition, immunological status and IL-1β profile in patients submitted to hematopoietic stem cell transplantation (HSCT). Fifty-four individuals submitted to HSCT were included. All patients received previous dental treatment and photobiomodulation (PBM) as the institutional OM preventive...
DNA damage-related proteins in smokers and non-smokers with oral cancer
Schuch,Lauren Frenzel; de Arruda,José Alcides Almeida; Viana,Karolina Skarlet Silva; Caldeira,Patrícia Carlos; Abreu,Mauro Henrique Nogueira GuimarãesAbstract: Tobacco smoking involves a high risk of human malignancies, including oral cancer, because it contains multiple carcinogens that cause genetic instability. Thus, a worse prognosis would be expected for cancer patients who are smokers. The aim of this study was to assess the DNA damage response through the expression of checkpoint kinase 2 (CHK2), H2A histone family member X (H2AX), and P53 among smoke...
Does smoking habit affect dendritic cell expression in oral squamous cell carci...
Barbieri,Silene; Schuch,Lauren Frenzel; Cascaes,Andreia Morales; Gomes,Ana Paula Neutzling; Tarquinio,Sandra Beatriz Chaves; Mesquita,Ricardo AlvesAbstract: The aim of this study was to determine the presence of immature CD1a+ and mature CD83+ dendritic cells in oral squamous cell carcinoma, to compare immunoreactivity between smokers and nonsmokers, and to correlate the results with histopathological grading. In this observational study, twenty-eight paraffin-embedded biopsies of oral squamous cell carcinoma were retrospectively retrieved and submitted t...