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Natural selection and recombination at host-interacting lipoprotein loci drive ...

Akther, Saymon; Mongodin, Emmanuel F.; Morgan, Richard D.; Di, Lia; Yang, Xiaohua; Golovchenko, Maryna; Rudenko, Natalie; Margos, Gabriele

Lyme disease, caused by spirochetes in the Borrelia burgdorferi sensu lato clade within the Borrelia genus, is transmitted by Ixodes ticks and is currently the most prevalent and rapidly expanding tick-borne disease in Europe and North America. We report complete genome sequences of 47 isolates that encompass all established species in this clade while highlighting the diversity of the widespread human pathogen...


The Population Structure of Borrelia lusitaniae Is Reflected by a Population Di...

Norte, Ana Cláudia; Boyer, Pierre H; Castillo-Ramirez, Santiago; Chvostáč, Michal; Brahami, Mohand O; Rollins, Robert E; Woudenberg, Tom

Populations of vector-borne pathogens are shaped by the distribution and movement of vector and reservoir hosts. To study what impact host and vector association have on tick-borne pathogens, we investigated the population structure of Borrelia lusitaniae using multilocus sequence typing (MLST). Novel sequences were acquired from questing ticks collected in multiple North African and European locations and were...


The population structure of Borrelia lusitaniae Is reflected by a population di...

Norte, Ana Cláudia; Boyer, Pierre H.; Castillo-Ramirez, Santiago; Chvostáč, Michal; Brahami, Mohand O.; Rollins, Robert E.; Woudenberg, Tom

Populations of vector-borne pathogens are shaped by the distribution and movement of vector and reservoir hosts. To study what impact host and vector association have on tick-borne pathogens, we investigated the population structure of Borrelia lusitaniae using multilocus sequence typing (MLST). Novel sequences were acquired from questing ticks collected in multiple North African and European locations and were...


Plasmid profile analysis of Portuguese Borrelia lusitaniae strains

Vitorino, Liliana; Margos, Gabriele; Zé-Zé, Líbia; Kurtenbach, Klaus; Collares-Pereira, Margarida

Plasmid profilesof2Portuguese Borrelia lusitaniae strains, oneisolatedfromahumanpatientandthe other onefroman Ixodes ricinus tick, wereobtainedbypulsed-fieldgelelectrophoresistoevaluatethe plasmid diversityineachstrain.Overall,amaximumof6plasmidsweredetectedthatrangedfrom 19 kbto76kb,revealingcompletelydifferentplasmidprofilesfromthosepreviouslydescribedforother genospecies of B. burgdorferi sensu lato,thecausa...


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