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Global guideline for the diagnosis and management of candidiasis: an initiative...

Cornely, Oliver A.; Sprute, Rosanne; Bassetti, Matteo; Chen, Sharon C-A; Groll, Andreas H.; Kurzai, Oliver; Lass-Flörl, Cornelia

Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised or critically ill. In contrast, mucocutaneous forms of candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individual...


Diagnosis of Breakthrough Fungal Infections in the Clinical Mycology Laboratory...

Jenks, Jeffrey D.; Gangneux, Jean-Pierre; Schwartz, Ilan S.; Alastruey-Izquierdo, Ana; Lagrou, Katrien; Thompson III, George R.; Lass-Flörl, Cornelia

Breakthrough invasive fungal infections (bIFI) cause significant morbidity and mortality. Their diagnosis can be challenging due to reduced sensitivity to conventional culture techniques, serologic tests, and PCR-based assays in patients undergoing antifungal therapy, and their diagnosis can be delayed contributing to poor patient outcomes. In this review, we provide consensus recommendations on behalf of the E...


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