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Short-term association between hot nights and mortality: a multicountry analysi...
Royé, Dominic; Sera, Francesco; Tobías, Aurelio; Hashizume, Masahiro; Honda, Yasushi; Kim, Ho; Vicedo-Cabrera, Ana Maria; Tong, Shilu; Lavigne, EricBackground: The rise in hot nights over recent decades and projections of further increases due to climate change underscores the critical need to understand their impact. This knowledge is essential for shaping public health strategies and guiding adaptation efforts. Despite their significance, research on the implications of hot nights remains limited. Objective: This study estimated the association between h...
Associations of ambient exposure to benzene, toluene, ethylbenzene, and xylene ...
Zhou, Lu; Xiong, Ying; Sera, Francesco; Vicedo-Cabrera, Ana Maria; Abrutzky, Rosana; Guo, Yuming; Tong, ShiluBackground: The presence of benzene, toluene, ethylbenzene, and xylene isomers (BTEX) in the environment is of increasing concern due to their toxicity and ubiquity. Although the adverse health effects of BTEX exposure have been documented, robust epidemiological evidence from large-scale, multicountry studies using advanced exposure assessment methodologies remains scarce. We aimed to assess the association of...
Estimating the urban heat-related mortality burden due to greenness: a global m...
Wu, Yao; Wen, Bo; Ye, Tingting; Huang, Wenzhong; Liu, Yanming; Gasparrini, Antonio; Sera, Francesco; Tong, Shilu; Lavigne, Eric; Roye, DominicBackground: Heat exposure poses a substantial public health threat. Increasing greenness has been suggested as a mitigation strategy due to its cooling effect and potential to modify the heat-mortality association. This study aimed to comprehensively estimate the effects of increased greenness on heat-related deaths. Methods: We applied a multistage meta-analytical approach to estimate the potential reduction i...
Rainfall events and daily mortality across 645 global locations: two stage time...
He, Cheng; Breitner-Busch, Susanne; Huber, Veronika; Chen, Kai; Zhang, Siqi; Gasparrini, Antonio; Bell, Michelle; Kan, Haidong; Royé, DominicObjective: To examine the associations between characteristics of daily rainfall (intensity, duration, and frequency) and all cause, cardiovascular, and respiratory mortality. Design: Two stage time series analysis. Setting: 645 locations across 34 countries or regions. Population: Daily mortality data, comprising a total of 109 954 744 all cause, 31 164 161 cardiovascular, and 11 817 278 respiratory deaths fro...
Temporal change in minimum mortality temperature under changing climate: A mult...
Yang, Daewon; Hashizume, Masahiro; Tobías, Aurelio; Honda, Yasushi; Roye, Dominic; Oh, Jaemin; Dang, Tran Ngoc; Kim, Yoonhee; Abrutzky, RosanaBackground: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries. Methods: Daily time-series data for mortality a...
Temperature frequency and mortality: Assessing adaptation to local temperature
Wu, Yao; Wen, Bo; Gasparrini, Antonio; Armstrong, Ben; Sera, Francesco; Lavigne, Eric; Li, Shanshan; Guo, Yuming; Overcenco, Ala; Urban, AlešAssessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...
Extreme Temperatures and Stroke Mortality: Evidence From a Multi-Country Analysis
Alahmad, Barrak; Khraishah, Haitham; Kamineni, Meghana; Royé, Dominic; Papatheodorou, Stefania I.; Vicedo-Cabrera, Ana Maria; Guo, Yuming; Lavigne, EricBackground: Extreme temperatures contribute significantly to global mortality. While previous studies on temperature and stroke-specific outcomes presented conflicting results, these studies were predominantly limited to single-city or single-country analyses. Their findings are difficult to synthesize due to variations in methodologies and exposure definitions. Methods: Within the Multi-Country Multi-City Netw...
Temporal variations in the short-term effects of ambient air pollution on cardi...
Schwarz, Maximilian; Peters, Annette; Stafoggia, Massimo; de'Donato, Francesca; Sera, Francesco; Bell, Michelle L; Guo, Yuming; Honda, YasushiBackground: Ambient air pollution, including particulate matter (such as PM10 and PM2·5) and nitrogen dioxide (NO2), has been linked to increases in mortality. Whether populations' vulnerability to these pollutants has changed over time is unclear, and studies on this topic do not include multicountry analysis. We evaluated whether changes in exposure to air pollutants were associated with changes in mortality ...
All-cause, cardiovascular, and respiratory mortality and wildfire-related ozone...
Chen, Gongbo; Guo, Yuming; Yue, Xu; Xu, Rongbin; Yu,Wenhua; Ye, Tingting; Tong, Shilu; Gasparrini, Antonio; Bell,Michelle L.; Armstrong, BenBackground: Wildfire activity is an important source of tropospheric ozone (O3) pollution. However, no study to date has systematically examined the associations of wildfire-related O3 exposure with mortality globally. Methods: We did a multicountry two-stage time series analysis. From the Multi-City Multi-Country (MCC) Collaborative Research Network, data on daily all-cause, cardiovascular, and respiratory dea...
Ozone-related acute excess mortality projected to increase in the absence of cl...
Domingo, Nina G.G.; Fiore, Arlene M.; Lamarque, Jean-Francois; Kinney, Patrick L.; Jiang, Leiwen; Gasparrini, Antonio; Breitner, Susanne; Lavigne, EricShort-term exposure to ground-level ozone in cities is associated with increased mortality and is expected to worsen with climate and emission changes. However, no study has yet comprehensively assessed future ozone-related acute mortality across diverse geographic areas, various climate scenarios, and using CMIP6 multi-model ensembles, limiting our knowledge on future changes in global ozone-related acute mort...