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Large increase in bloodstream infections with carbapenem-resistant Acinetobacte...

Kinross, Pete; Gagliotti, Carlo; Merk, Hanna; Plachouras, Diamantis; Monnet, Dominique L; Högberg, Liselotte Diaz; EARS-Net Study Group

Bloodstream infections (BSIs) with Acinetobacter species commonly have poor outcomes, especially in intensive care unit (ICU) patients [1]. Acinetobacter spp. is intrinsically resistant to many antimicrobials, and additional acquired resistance further complicates the treatment of serious infections in already vulnerable patient groups. Recent data from the European Antimicrobial Resistance Surveillance Network...


Decreasing and stabilising trends of antimicrobial consumption and resistance i...

Peñalva, Germán; Högberg, Liselotte Diaz; Weist, Klaus; Vlahović-Palčevski, Vera; Heuer, Ole; Monnet, Dominique L; ESAC-Net study group

Investments to reduce the spread of antimicrobial resistance (AMR) in the European Union have been made, including efforts to strengthen prudent antimicrobial use. Using segmented regression, we report decreasing and stabilising trends in data reported to the European Surveillance of Antimicrobial Consumption Network and stabilising trends in data reported to the European Antimicrobial Resistance Surveillance N...


Attributable deaths and disability-adjusted life-years caused by infections wit...

Cassini, Alessandro; Högberg, Liselotte Diaz; Plachouras, Diamantis; Quattrocchi, Annalisa; Hoxha, Ana; Simonsen, Gunnar Skov; Colomb-Cotinat, Mélanie

Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by antibiotic-resistant bacteria of public health concern in countries of the EU and European Economic Area (EEA) in 2015, measured in number of cases, attributable death...


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