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Evaluation of the immune response to CRA and FRA recombinant antigens of Trypan...

Pereira,Valéria Rêgo Alves; Lorena,Virginia Maria Barros de; Nakazawa,Mineo; Silva,Ana Paula Galvão da; Montarroyos,Ulisses; Correa-Oliveira,Rodrigo

Humoral and cellular immune responses were evaluated in 44 C57BL/6 mice immunized with the Trypanosoma cruzi recombinant antigens CRA and FRA. Both antigens induced cutaneous immediate-type hypersensitivity response. The levels of IgG1, IgG2a, IgG2b and IgG3 were high in CRA immunized mice. IgG3 was the predominant isotype. Although no difference in antibody levels was observed in FRA-immunized mice when compar...

Date: 2003   |   Origin: Oasisbr
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