6 documents found, page 1 of 1
Switch from a type 2 to a type 1 T helper cell response and cure of established...
Nabors, Gary S.; Afonso, Luís Carlos Crocco; Farrell, Jay P.; Scott, PhillipSuccessful treatment in allergic, autoimmune, and infectious diseases often requires altering the nature of a detrimental immune response mediated by a particular CD4+ T helper (Th) cell subset. While several factors contribute to the development of CD4+ Thi and Th2 cells, the requirements for switching an established response are not understood. Here we use infection with Leishmania major as a model to investi...
Infection with Leishmania major induces interleukin-12 production in vivo.
Vieira, Leda Quercia; Hondowicz, Brian D.; Afonso, Luís Carlos Crocco; Wysocka, Maria; Trinchieri, Giorgio; Scott, PhillipExperimental infections of mice with the protozoan parasite Leishmania major provide an excellent model for defining the conditions required for generation of CD4 ÷ Thl and Th2 cells in vivo. Since interleukin-12 (IL-12) has been implicated in the development of Thl cells, we investigated whether L. major stimulates IL-12 production in vitro or in vivo. Surprisingly, macrophages cultured in vitro failed to prod...
Immunologic response and memory T cells in subjects cured of tegumentary leishm...
Carvalho, Augusto M.; Magalhães, Andréa; Carvalho, Lucas Pedreira de; Bacellar, Maria Olívia Amado Ramos; Scott, Phillipp. 1-8; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-07T14:31:03Z No. of bitstreams: 1 1471-2334-13-529.pdf: 588230 bytes, checksum: 97d4a8ab8afd2f9b072d25708780c334 (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:19:34Z (GMT) No. of bitstreams: 1 1471-2334-13-529.pdf: 588230 bytes, checksum: 97d4a8ab8afd2f9b072d25708780c334 (MD5); Made available ...
Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis
Novais, Fernanda O.; Carvalho, Lucas Pedreira de; Graff, Joel W.; Beiting, Daniel P.; Ruthel, Gordon; Roos, David S.; Betts, Michael R.p. 1-11; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-20T14:50:08Z No. of bitstreams: 1 10.1371-journal.ppat.1003504.pdf: 1217813 bytes, checksum: 9fcc505b5db15908f14a41556227d1fd (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-05-26T13:45:57Z (GMT) No. of bitstreams: 1 10.1371-journal.ppat.1003504.pdf: 1217813 bytes, checksum: 9fcc505b5db15908f14a41556227d1...
IL-17 Mediates Immunopathology in the Absence of IL-10 Following Leishmania maj...
Lombana, Claudia Gonzalez; Gimblet, Ciara; Bacellar, Maria Olívia Amado Ramos; Oliveira, Walker W.; Passos, Sara; Carvalho, Lucas Pedreira dep. 1-14; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-12-01T11:23:49Z No. of bitstreams: 1 Claudia Gonzalez Lombana.pdf: 1907722 bytes, checksum: cc9acc0548f3518beac68821242128f2 (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-12-01T11:51:48Z (GMT) No. of bitstreams: 1 Claudia Gonzalez Lombana.pdf: 1907722 bytes, checksum: cc9acc0548f3518beac68821242128...
Interleukin 17 production among patients with American cutaneous leishmaniasis
Bacellar, Maria Olívia Amado Ramos; Faria, Daniela; Nascimento, Márcia; Cardoso, Thiago M.; Gollob, Kenneth John; Dutra, Walderez OrnelasTexto completo: acesso restrito. p. 75-78; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-10-07T15:20:03Z No. of bitstreams: 1 J Infect Dis.-2009-Bacellar-75-8.pdf: 2559395 bytes, checksum: b2f2accf01ca1dec22f998e0ab998ec0 (MD5); Approved for entry into archive by Rodrigo Meirelles(rodrigomei@ufba.br) on 2013-10-09T19:40:55Z (GMT) No. of bitstreams: 1 J Infect Dis.-2009-Bacellar-75-8.pdf: 2559395 byte...