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Nanomaterial-based scaffolds endowed with halochromic properties for skin heali...

Ribeiro, Ana R. M.; Oliveira, Bruna A. S.; Barbosa, Ana Isabel; Seabra, Catarina L.; Reis, Salette; Felgueiras, Helena Prado

Recently, biomedical engineering has seen significant advancements in nanomaterial-based scaffolds for tissue engineering and wound healing. Incorporating halochromic properties within these scaffolds has garnered substantial interest due to their real-time monitoring abilities for accessing tissue growth and regeneration. This review presents a comprehensive analysis of recent advancements in nanomaterial-base...


Sodium alginate/polycaprolactone co-axial wet-spun microfibers modified with N-...

Miranda, Catarina S.; Silva, A. Francisca G.; Seabra, Catarina L.; Reis, Salette; Silva, Maria Manuela; Pereira-Lima, Sílvia M. M. A.

In chronic wound (CW) scenarios, Staphylococcus aureus-induced infections are very prevalent. This leads to abnormal inflammatory processes, in which proteolytic enzymes, such as human neutrophil elastase (HNE), become highly expressed. Alanine-Alanine-Proline-Valine (AAPV) is an antimicrobial tetrapeptide capable of suppressing the HNE activity, restoring its expression to standard rates. Here, we proposed the...


Uncovering Akkermansia muciniphila resilience or susceptibility to different te...

Machado, Daniela; Almeida, Diana; Seabra, Catarina L.; Andrade, José Carlos; Gomes, Ana Maria; Freitas, Ana Cristina

Data regarding Akkermansia muciniphila viability under stress remains scarce despite its beneficial potential. Therefore, the main goal was to assess A. muciniphila culturability when exposed to different temperatures, atmospheres and gastrointestinal simulated conditions. Cultivable cell numbers A. muciniphila remain high after refrigerated and room temperatures oxygen exposure, and gastrointestinal passage.


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